Reactome | ATP13A1 transports Mn2+ from cytosol to ER lumen

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ATP13A1 transports Mn2+ from cytosol to ER lumen Show undefined attributes

authored	[InstanceEdit:5692438] Jassal, Bijay, 2015-05-12
catalystActivity	[CatalystActivity:5692497] ABC-type manganese transporter activity of ATP13A1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:5692473] Jassal, Bijay, 2015-05-12
crossReference	[DatabaseIdentifier:12668227] RHEA:17365
dbId	5692462
displayName	ATP13A1 transports Mn2+ from cytosol to ER lumen
edited	[InstanceEdit:5692438] Jassal, Bijay, 2015-05-12
eventOf	[Pathway:R-HSA-936837] Ion transport by P-type ATPases - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29418] Mn2+ [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5692463] The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	ATP13A1 transports Mn2+ from cytosol to ER lumen
orthologousEvent	[Reaction:R-PFA-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Plasmodium falciparum [Reaction:R-SCE-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Saccharomyces cerevisiae [Reaction:R-SPO-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Schizosaccharomyces pombe [Reaction:R-DDI-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Dictyostelium discoideum [Reaction:R-CEL-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Caenorhabditis elegans [Reaction:R-DME-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Drosophila melanogaster [Reaction:R-GGA-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Gallus gallus [Reaction:R-XTR-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Xenopus tropicalis [Reaction:R-DRE-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Danio rerio [Reaction:R-SSC-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Sus scrofa [Reaction:R-BTA-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Bos taurus [Reaction:R-CFA-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Canis familiaris [Reaction:R-RNO-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Rattus norvegicus [Reaction:R-MMU-5692462] ATP13A1 transports Mn2+ from cytosol to ER lumen - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-1981162] Mn2+ [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5692462
summation	[Summation:5692455] Manganese-transporting ATPase 13A1 (ATP13A1) mediates the tr...

Referrals

(hasEvent)

[Pathway:R-HSA-936837] Ion transport by P-type ATPases