Reactome | XPC binds RAD23 and CETN2

Schema > Reaction > Entries

XPC binds RAD23 and CETN2 Show undefined attributes

authored	[InstanceEdit:110274] Gopinathrao, G, 2004-01-29 18:08:32 [InstanceEdit:110275] Hoeijmakers, JH, 2004-01-29 18:08:33 [InstanceEdit:5691003] Orlic-Milacic, Marija, 2015-05-04
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5691003] Orlic-Milacic, Marija, 2015-05-04
dbId	5691004
deleted	[Deleted:6793524] Deletion of instance: 109948
displayName	XPC binds RAD23 and CETN2
edited	[InstanceEdit:5691003] Orlic-Milacic, Marija, 2015-05-04
eventOf	[Pathway:R-HSA-5696394] DNA Damage Recognition in GG-NER - Homo sapiens
followingEvent	[Reaction:R-HSA-5691006] XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-4570490] CETN2 [nucleoplasm] [CandidateSet:R-HSA-5688130] RAD23 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-67441] XPC [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5688128] Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23 [LiteratureReference:5688134] A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein [LiteratureReference:5688127] Centrosome protein centrin 2/caltractin 1 is part of the xeroderma pigmentosum group C complex that initiates global genome nucleotide excision repair [LiteratureReference:5688129] Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	XPC binds RAD23 and CETN2
orthologousEvent	[Reaction:R-GGA-353524] XP-C binds to RAD23B forming a heterodimer - Gallus gallus [Reaction:R-MMU-5691004] XPC binds RAD23 and CETN2 - Mus musculus [Reaction:R-PFA-5691004] XPC binds RAD23 and CETN2 - Plasmodium falciparum [Reaction:R-SPO-5691004] XPC binds RAD23 and CETN2 - Schizosaccharomyces pombe [Reaction:R-DDI-5691004] XPC binds RAD23 and CETN2 - Dictyostelium discoideum [Reaction:R-CEL-5691004] XPC binds RAD23 and CETN2 - Caenorhabditis elegans [Reaction:R-DME-5691004] XPC binds RAD23 and CETN2 - Drosophila melanogaster [Reaction:R-GGA-5691004] XPC binds RAD23 and CETN2 - Gallus gallus [Reaction:R-XTR-5691004] XPC binds RAD23 and CETN2 - Xenopus tropicalis [Reaction:R-DRE-5691004] XPC binds RAD23 and CETN2 - Danio rerio [Reaction:R-BTA-5691004] XPC binds RAD23 and CETN2 - Bos taurus [Reaction:R-CFA-5691004] XPC binds RAD23 and CETN2 - Canis familiaris [Reaction:R-RNO-5691004] XPC binds RAD23 and CETN2 - Rattus norvegicus
output	[Complex:R-HSA-5691010] XPC:RAD23:CETN2 [nucleoplasm]
releaseDate	2004-03-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6790576] Fousteri, Maria, 2015-08-03
revised	[InstanceEdit:5691003] Orlic-Milacic, Marija, 2015-05-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5691004
summation	[Summation:5690976] XPC is mutated in individuals with xeroderma pigmentosum fro...

Referrals

(replacementInstances)	[Deleted:6793524] Deletion of instance: 109948
(hasEvent)	[Pathway:R-HSA-5696394] DNA Damage Recognition in GG-NER
(precedingEvent)	[Reaction:R-HSA-5691006] XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site

Cite Us!