Reactome | SFTPAs translocate from ER membrane to extracellular region

Schema > BlackBoxEvent > Entries

SFTPAs translocate from ER membrane to extracellular region Show undefined attributes

authored	[InstanceEdit:5685640] Jassal, Bijay, 2015-03-27
category	uncertain
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:984] extracellular region
created	[InstanceEdit:5685640] Jassal, Bijay, 2015-03-27
dbId	5685649
diseaseReaction	[FailedReaction:R-HSA-5687875] Defective SFTPA2 does not translocate from ER membrane to extracellular region - Homo sapiens
displayName	SFTPAs translocate from ER membrane to extracellular region
edited	[InstanceEdit:5685640] Jassal, Bijay, 2015-03-27
eventOf	[Pathway:R-HSA-5683826] Surfactant metabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-5687284] DMBT1 binds SFTPD 12mer, SFTPAs - Homo sapiens [Reaction:R-HSA-5686335] CSF2RA:CSF2RB binds SFTPs - Homo sapiens [Reaction:R-HSA-5686301] PALM-C100-CKAP4 binds SFTPAs - Homo sapiens
input	[DefinedSet:R-HSA-5683863] SFTPAs [endoplasmic reticulum membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5687871] Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	SFTPAs translocate from ER membrane to extracellular region
orthologousEvent	[BlackBoxEvent:R-PFA-5685649] SFTPAs translocate from ER membrane to extracellular region - Plasmodium falciparum [BlackBoxEvent:R-DME-5685649] SFTPAs translocate from ER membrane to extracellular region - Drosophila melanogaster [BlackBoxEvent:R-GGA-5685649] SFTPAs translocate from ER membrane to extracellular region - Gallus gallus [BlackBoxEvent:R-DRE-5685649] SFTPAs translocate from ER membrane to extracellular region - Danio rerio [BlackBoxEvent:R-BTA-5685649] SFTPAs translocate from ER membrane to extracellular region - Bos taurus [BlackBoxEvent:R-CFA-5685649] SFTPAs translocate from ER membrane to extracellular region - Canis familiaris [BlackBoxEvent:R-RNO-5685649] SFTPAs translocate from ER membrane to extracellular region - Rattus norvegicus [BlackBoxEvent:R-MMU-5685649] SFTPAs translocate from ER membrane to extracellular region - Mus musculus
output	[DefinedSet:R-HSA-5685647] SFTPAs [extracellular region]
precedingEvent	[BlackBoxEvent:R-HSA-5683879] SFTPA genes produce SFTPA proteins - Homo sapiens
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6791021] D'Eustachio, Peter, 2015-08-17
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-5685649
summation	[Summation:5687986] The pulmonary collectins, surfactant proteins A1, A2, A3 and...
updateTrackers	[UpdateTracker:9778737] Update Tracker - [BlackBoxEvent:5685649] SFTPAs translocate from ER membrane to extracellular region - v67:[removeInput, removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9778737] Update Tracker - [BlackBoxEvent:5685649] SFTPAs translocate from ER membrane to extracellular region - v67:[removeInput, removeOutput]
(normalReaction)	[FailedReaction:R-HSA-5687875] Defective SFTPA2 does not translocate from ER membrane to extracellular region
(precedingEvent)	[Reaction:R-HSA-5687284] DMBT1 binds SFTPD 12mer, SFTPAs [Reaction:R-HSA-5686301] PALM-C100-CKAP4 binds SFTPAs [Reaction:R-HSA-5686335] CSF2RA:CSF2RB binds SFTPs
(hasEvent)	[Pathway:R-HSA-5683826] Surfactant metabolism