Reactome | RAD51AP1 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

RAD51AP1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-5685655] BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] - Homo sapiens
consumedByEvent	[FailedReaction:R-HSA-9704408] Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in binding to BRCA2/RAD51/RAD51C - Homo sapiens [FailedReaction:R-HSA-9701199] Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of BRCA1 in PALB2 binding - Homo sapiens [FailedReaction:R-HSA-9709601] Defective recruitment of BRCA2 and RAD51 due to loss of BRCA2 function in PALB2 binding - Homo sapiens [FailedReaction:R-HSA-9704330] Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in BRCA1 binding - Homo sapiens [Reaction:R-HSA-5693620] D-loop formation mediated by PALB2, BRCA2 and RAD51 - Homo sapiens
created	[InstanceEdit:5685300] Orlic-Milacic, Marija, 2015-03-26
dbId	5685301
displayName	RAD51AP1 [nucleoplasm]
endCoordinate	352
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-5685301] Rad51ap1 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-5685301] Rad51ap1 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-5685301] RAD51AP1 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-5685301] RAD51AP1 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-5685301] RAD51AP1 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-5685301] rad51ap1 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-5685301] rad51ap1 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-5685301] RAD51AP1 [nucleoplasm] - Gallus gallus
maxDepth	1
name	RAD51AP1 RAD51-associated protein 1 PIR51 RAD51-interacting protein
producedByEvent	[BlackBoxEvent:R-HSA-5686483] Resolution of Holliday junctions cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) - Homo sapiens [BlackBoxEvent:R-HSA-5686469] Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2 - Homo sapiens [Reaction:R-HSA-5686410] BLM mediates dissolution of double Holliday junction - Homo sapiens [Reaction:R-HSA-5693589] D-loop dissociation and strand annealing - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q96B01] UniProt:Q96B01 RAD51AP1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-5685301
startCoordinate	1

Referrals

(input)	[FailedReaction:R-HSA-9704330] Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in BRCA1 binding [FailedReaction:R-HSA-9704408] Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in binding to BRCA2/RAD51/RAD51C [FailedReaction:R-HSA-9701199] Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of BRCA1 in PALB2 binding [FailedReaction:R-HSA-9709601] Defective recruitment of BRCA2 and RAD51 due to loss of BRCA2 function in PALB2 binding [Reaction:R-HSA-5693620] D-loop formation mediated by PALB2, BRCA2 and RAD51
(output)	[Reaction:R-HSA-5686410] BLM mediates dissolution of double Holliday junction [BlackBoxEvent:R-HSA-5686483] Resolution of Holliday junctions cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) [Reaction:R-HSA-5693589] D-loop dissociation and strand annealing [BlackBoxEvent:R-HSA-5686469] Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2
(hasComponent)	[Complex:R-HSA-5685655] BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm]

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