Reactome | hyperphosphorylated RAF1 [plasma membrane]

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hyperphosphorylated RAF1 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5675195] Rothfels, Karen, 2015-02-15
dbId	5675193
displayName	hyperphosphorylated RAF1 [plasma membrane]
endCoordinate	648
hasModifiedResidue	[ModifiedResidue:109785] O-phospho-L-serine at 621 [ModifiedResidue:109791] O4'-phospho-L-tyrosine at 341 [ModifiedResidue:444234] O-phospho-L-serine at 338 [ModifiedResidue:5672662] O-phospho-L-threonine at 491 [ModifiedResidue:5672663] O-phospho-L-serine at 494 [ModifiedResidue:5675178] O-phospho-L-serine at 29 [ModifiedResidue:5675183] O-phospho-L-serine at 43 [ModifiedResidue:109784] O-phospho-L-serine at 259 [ModifiedResidue:5675179] O-phospho-L-serine at 296 [ModifiedResidue:5675182] O-phospho-L-serine at 301 [ModifiedResidue:5675185] O-phospho-L-serine at 642
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-5675193] phospho-hyperphosphorylated RAF1 [plasma membrane] - Mus musculus [EntityWithAccessionedSequence:R-RNO-5675193] phospho-hyperphosphorylated RAF1 [plasma membrane] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-5675193] phospho-RAF1 [plasma membrane] - Canis familiaris [EntityWithAccessionedSequence:R-DRE-5675193] phospho-hyperphosphorylated RAF1 [plasma membrane] - Danio rerio [EntityWithAccessionedSequence:R-XTR-5675193] phospho-hyperphosphorylated RAF1 [plasma membrane] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-5675193] phospho-hyperphosphorylated RAF1 [plasma membrane] - Gallus gallus [EntityWithAccessionedSequence:R-DME-5675193] phospho-hyperphosphorylated RAF1 [plasma membrane] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-5675193] phospho-hyperphosphorylated RAF1 [plasma membrane] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-5675193] phospho-hyperphosphorylated RAF1 [plasma membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-5675193-2] phospho-hyperphosphorylated RAF1 [plasma membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-5675193-3] phospho-hyperphosphorylated RAF1 [plasma membrane] - Dictyostelium discoideum [DefinedSet:R-DDI-5675193-4] Homologues of hyperphosphorylated RAF1 [plasma membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-PFA-5675193] phospho-hyperphosphorylated RAF1 [plasma membrane] - Plasmodium falciparum [EntityWithAccessionedSequence:R-PFA-5675193-2] phospho-hyperphosphorylated RAF1 [plasma membrane] - Plasmodium falciparum [EntityWithAccessionedSequence:R-PFA-5675193-3] phospho-hyperphosphorylated RAF1 [plasma membrane] - Plasmodium falciparum [DefinedSet:R-PFA-5675193-4] Homologues of hyperphosphorylated RAF1 [plasma membrane] - Plasmodium falciparum
maxDepth	1
name	hyperphosphorylated RAF1 p-S29,S43,S259,S296,S301,S338,Y341,T491,S494,S621,S642 RAF1 RAF proto-oncogene serine/threonine-protein kinase Raf-1 C-RAF cRaf
positivelyRegulates	[PositiveRegulation:R-HSA-5675437] Positive regulation by 'hyperphosphorylated RAF1 [plasma membrane]'
producedByEvent	[Reaction:R-HSA-5675194] Activated MAPK phosphorylates RAF1 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P04049] UniProt:P04049 RAF1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-5675193
startCoordinate	1

Referrals

(output)	[Reaction:R-HSA-5675194] Activated MAPK phosphorylates RAF1
(regulator)	[PositiveRegulation:R-HSA-5675437] Positive regulation by 'hyperphosphorylated RAF1 [plasma membrane]'

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