Reactome | Activated CIT binds KIF14 and PRC1

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Activated CIT binds KIF14 and PRC1 Show undefined attributes

authored	[InstanceEdit:5628889] Orlic-Milacic, Marija, 2014-10-24 [InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:5671968] Orlic-Milacic, Marija, 2015-02-03
dbId	5671970
displayName	Activated CIT binds KIF14 and PRC1
edited	[InstanceEdit:5671747] Orlic-Milacic, Marija, 2015-02-02
eventOf	[Pathway:R-HSA-5625900] RHO GTPases activate CIT - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-1629804] KIF14 [cytosol] [EntityWithAccessionedSequence:R-HSA-264441] PRC1 [cytosol] [Complex:R-HSA-5625899] RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5625921] KIF14 and citron kinase act together to promote efficient cytokinesis [LiteratureReference:5625944] Citron kinase mediates transition from constriction to abscission through its coiled-coil domain [LiteratureReference:5625914] Citron kinase controls a molecular network required for midbody formation in cytokinesis
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	Activated CIT binds KIF14 and PRC1
orthologousEvent	[Reaction:R-GGA-5671970] Activated CIT binds KIF14 and PRC1 - Gallus gallus [Reaction:R-DME-5671970] Activated CIT binds KIF14 and PRC1 - Drosophila melanogaster [Reaction:R-BTA-5671970] Activated CIT binds KIF14 and PRC1 - Bos taurus [Reaction:R-CFA-5671970] Activated CIT binds KIF14 and PRC1 - Canis familiaris [Reaction:R-RNO-5671970] Activated CIT binds KIF14 and PRC1 - Rattus norvegicus [Reaction:R-MMU-5671970] Activated CIT binds KIF14 and PRC1 - Mus musculus
output	[Complex:R-HSA-5671969] RHOA,RHOB,RHOC,RAC1:GTP:CIT:KIF14:PRC1 [plasma membrane]
precedingEvent	[Reaction:R-HSA-5625901] CIT (citron kinase) binds activated RHOA, RHOB, RHOC and RAC1 - Homo sapiens
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5671970
summation	[Summation:5671967] Activated citron kinase (CIT) binds KIF14 and PRC1 at the ce...

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(hasEvent)

[Pathway:R-HSA-5625900] RHO GTPases activate CIT