Activated citron kinase (CIT) binds KIF14 and PRC1 at the central spindle and mid-body and this evolutionarily conserved interaction is necessary for the formation of the cleavage furrow and completion of cytokinesis. The C-terminal part of the CIT coiled-coil domain binds RHO GTPase while the N-terminal part of the CIT coiled coil domain binds KIF14 (Gruneberg et al. 2006, Watanabe et al. 2013, Bassi et al. 2013).
Bassi, ZI, D'Avino, PP, Riparbelli, MG, Audusseau, M, Callaini, G
Narumiya, S, Ishizaki, T, De Zan, T, Watanabe, S
Chalamalasetty, RB, Neef, R, Barr, FA, Nigg, EA, Chan, EH, Gruneberg, U, Li, X
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