Activated citron kinase (CIT) binds KIF14 and PRC1 at the central spindle and mid-body and this evolutionarily conserved interaction is necessary for the formation of the cleavage furrow and completion of cytokinesis. The C-terminal part of the CIT coiled-coil domain binds RHO GTPase while the N-terminal part of the CIT coiled coil domain binds KIF14 (Gruneberg et al. 2006, Watanabe et al. 2013, Bassi et al. 2013).
Watanabe, S, De Zan, T, Ishizaki, T, Narumiya, S
Bassi, ZI, Audusseau, M, Riparbelli, MG, Callaini, G, D'Avino, PP
Gruneberg, U, Neef, R, Li, X, Chan, EH, Chalamalasetty, RB, Nigg, EA, Barr, FA
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