Reactome | FGFBPs bind FGFs

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FGFBPs bind FGFs Show undefined attributes

authored	[InstanceEdit:5655664] Rothfels, Karen, 2014-12-08
category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:5656066] Rothfels, Karen, 2014-12-10
dbId	5656070
displayName	FGFBPs bind FGFs
edited	[InstanceEdit:5662959] Rothfels, Karen, 2015-01-14
eventOf	[Pathway:R-HSA-190377] FGFR2b ligand binding and activation - Homo sapiens
input	[DefinedSet:R-HSA-5656048] FGF2,7,10,22 [extracellular region] [CandidateSet:R-HSA-5656046] FGFBP [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5656069] Characterization and molecular cloning of a putative binding protein for heparin-binding growth factors [LiteratureReference:5656068] Enhancement of fibroblast growth factor (FGF) activity by an FGF-binding protein [LiteratureReference:190922] The fibroblast growth factor-binding protein FGF-BP [LiteratureReference:5656067] The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	FGFBPs bind FGFs
orthologousEvent	[Reaction:R-MMU-5656070] FGFBPs bind FGFs - Mus musculus [Reaction:R-GGA-5656070] FGFBPs bind FGFs - Gallus gallus [Reaction:R-XTR-5656070] FGFBPs bind FGFs - Xenopus tropicalis [Reaction:R-DRE-5656070] FGFBPs bind FGFs - Danio rerio [Reaction:R-SSC-5656070] FGFBPs bind FGFs - Sus scrofa [Reaction:R-BTA-5656070] FGFBPs bind FGFs - Bos taurus [Reaction:R-CFA-5656070] FGFBPs bind FGFs - Canis familiaris [Reaction:R-RNO-5656070] FGFBPs bind FGFs - Rattus norvegicus
output	[Complex:R-HSA-5656071] FGFBP:FGF [extracellular region]
releaseDate	2015-06-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8851383] Nishimura, Tatsunori, 2016-01-06 [InstanceEdit:8865033] Gotoh, N, 2016-03-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5656070
summation	[Summation:5656065] Fibroblast growth factor binding proteins (FGFBPs) are extra...
updateTrackers	[UpdateTracker:9783549] Update Tracker - [Reaction:5656070] FGFBPs bind FGFs - v56:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9783549] Update Tracker - [Reaction:5656070] FGFBPs bind FGFs - v56:[modifyText]
(hasEvent)	[Pathway:R-HSA-190377] FGFR2b ligand binding and activation