Reactome | Activated FGFR4 mutants [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5655237] Activated FGFR4 mutants:p-4Y-PLCG1 [plasma membrane] - Homo sapiens [Complex:R-HSA-5655279] Activated FGFR4 mutants:PLCG1 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5655313] Activated FGFR4 mutants bind PLCG1 - Homo sapiens [Reaction:R-HSA-5655351] Activated FGFR4 mutants bind FRS2 - Homo sapiens
created	[InstanceEdit:5655319] Rothfels, Karen, 2014-12-05
crossReference	[DatabaseIdentifier:12020828] Mondo:0005497
dbId	5655280
disease	[Disease:1500689] cancer [Disease:2032940] bone development disease
displayName	Activated FGFR4 mutants [plasma membrane]
hasMember	[CandidateSet:R-HSA-2038945] Activated FGFR4 enhanced kinase mutants [plasma membrane] - Homo sapiens [Complex:R-HSA-2011990] Activated FGFR4 Y367C mutant [plasma membrane] - Homo sapiens
inDisease	true
maxDepth	4
name	Activated FGFR4 mutants
producedByEvent	[Reaction:R-HSA-5655336] p-4Y-PLCG1 dissociates from activated FGFR4 mutants - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-5655280

(output)	[Reaction:R-HSA-5655336] p-4Y-PLCG1 dissociates from activated FGFR4 mutants
(hasComponent)	[Complex:R-HSA-5655237] Activated FGFR4 mutants:p-4Y-PLCG1 [plasma membrane] [Complex:R-HSA-5655279] Activated FGFR4 mutants:PLCG1 [plasma membrane] [Complex:R-HSA-5655308] Activated FGFR4 mutants:p-FRS2 [plasma membrane] [Complex:R-HSA-5655299] Activated FGFR4 mutants:FRS2 [plasma membrane]
(input)	[Reaction:R-HSA-5655313] Activated FGFR4 mutants bind PLCG1 [Reaction:R-HSA-5655351] Activated FGFR4 mutants bind FRS2
(diseaseEntity)	[EntityFunctionalStatus:5655335] gain_of_function of Activated FGFR4 mutants [plasma membrane]