Reactome | Activated FGFR3 point and translocation mutants [plasma membrane]

Schema > DefinedSet > Entries

Activated FGFR3 point and translocation mutants [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5655321] Activated FGFR3 point and translocation mutants:p-4Y-PLCG1 [plasma membrane] - Homo sapiens [Complex:R-HSA-5655305] Activated FGFR3 point and translocation mutants: PLCG1 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5655244] Activated FGFR3 point and translocation mutants bind PLCG1 - Homo sapiens
created	[InstanceEdit:5655319] Rothfels, Karen, 2014-12-05
crossReference	[DatabaseIdentifier:12020828] Mondo:0005497
dbId	5655234
disease	[Disease:1500689] cancer [Disease:2032940] bone development disease
displayName	Activated FGFR3 point and translocation mutants [plasma membrane]
hasMember	[CandidateSet:R-HSA-2038377] Activated FGFR3 t(4;14) translocation mutants [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-2033358] Activated FGFR3 mutants with enhanced kinase activity [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-2012020] Activated FGFR3 cysteine mutants [plasma membrane] - Homo sapiens [Complex:R-HSA-2011989] Activated FGFR3c P250R mutant [plasma membrane] - Homo sapiens
inDisease	true
maxDepth	4
modified	[InstanceEdit:9753869] Rothfels, Karen, 2021-09-16
name	Activated FGFR3 point and translocation mutants
producedByEvent	[Reaction:R-HSA-5655247] p-4Y-PLCG1 dissociates from activated FGFR3 point and translocation mutants - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-5655234
updateTrackers	[UpdateTracker:9902851] Update Tracker - [DefinedSet:5655234] Activated FGFR3 point and translocation mutants [plasma membrane] - v79:[modifyName] [UpdateTracker:9893659] Update Tracker - [DefinedSet:5655234] Activated FGFR3 point and translocation mutants [plasma membrane] - v56:[updateContainedMemberOrCandidate]

Referrals

(updatedInstance)	[UpdateTracker:9902851] Update Tracker - [DefinedSet:5655234] Activated FGFR3 point and translocation mutants [plasma membrane] - v79:[modifyName] [UpdateTracker:9893659] Update Tracker - [DefinedSet:5655234] Activated FGFR3 point and translocation mutants [plasma membrane] - v56:[updateContainedMemberOrCandidate]
(input)	[Reaction:R-HSA-5655244] Activated FGFR3 point and translocation mutants bind PLCG1
(diseaseEntity)	[EntityFunctionalStatus:9757294] gain_of_function of Activated FGFR3 point and translocation mutants [plasma membrane]
(hasComponent)	[Complex:R-HSA-5655305] Activated FGFR3 point and translocation mutants: PLCG1 [plasma membrane] [Complex:R-HSA-5655321] Activated FGFR3 point and translocation mutants:p-4Y-PLCG1 [plasma membrane]
(output)	[Reaction:R-HSA-5655247] p-4Y-PLCG1 dissociates from activated FGFR3 point and translocation mutants

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