Reactome | Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane]

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5655217] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5655263] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA - Homo sapiens
created	[InstanceEdit:5655219] Rothfels, Karen, 2014-12-05
crossReference	[DatabaseIdentifier:12020828] Mondo:0005497
dbId	5655218
disease	[Disease:1500689] cancer [Disease:2032940] bone development disease
displayName	Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane]
hasComponent	[Complex:R-HSA-5655216] Activated FGFR1 mutants:p-FRS2 [plasma membrane] [Complex:R-HSA-179864] GRB2:GAB1:PIK3R1 [cytosol]
inDisease	true
includedLocation	[Compartment:70101] cytosol
isChimeric	false
maxDepth	7
name	Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1
producedByEvent	[Reaction:R-HSA-5655240] Activated FGFR1 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5655218
updateTrackers	[UpdateTracker:9898753] Update Tracker - [Complex:5655218] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] - v64:[updateContainedComponent] [UpdateTracker:9893693] Update Tracker - [Complex:5655218] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] - v56:[updateContainedComponent] [UpdateTracker:9898237] Update Tracker - [Complex:5655218] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] - v63:[updateContainedComponent] [UpdateTracker:9897129] Update Tracker - [Complex:5655218] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] - v61:[updateContainedComponent] [UpdateTracker:9965033] Update Tracker - [Complex:5655218] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] - v94:[updateContainedComponent]

(updatedInstance)	[UpdateTracker:9898753] Update Tracker - [Complex:5655218] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] - v64:[updateContainedComponent] [UpdateTracker:9893693] Update Tracker - [Complex:5655218] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] - v56:[updateContainedComponent] [UpdateTracker:9898237] Update Tracker - [Complex:5655218] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] - v63:[updateContainedComponent] [UpdateTracker:9897129] Update Tracker - [Complex:5655218] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] - v61:[updateContainedComponent] [UpdateTracker:9965033] Update Tracker - [Complex:5655218] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] - v94:[updateContainedComponent]
(output)	[Reaction:R-HSA-5655240] Activated FGFR1 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1
(hasComponent)	[Complex:R-HSA-5655217] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]
(input)	[Reaction:R-HSA-5655263] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA
(diseaseEntity)	[EntityFunctionalStatus:5655349] gain_of_function of Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane]

Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] Show undefined attributes

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