Reactome | Downstream signaling of activated FGFR4

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Downstream signaling of activated FGFR4 Show undefined attributes

authored	[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18
created	[InstanceEdit:5654713] Rothfels, Karen, 2014-12-03
dbId	5654716
deleted	[Deleted:5655585] Deletion of instance: 190333
displayName	Downstream signaling of activated FGFR4
edited	[InstanceEdit:500337] Jupe, S, 2010-02-03
eventOf	[Pathway:R-HSA-5654743] Signaling by FGFR4 - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-HSA-5654712] FRS-mediated FGFR4 signaling - Homo sapiens [Pathway:R-HSA-5654228] Phospholipase C-mediated cascade; FGFR4 - Homo sapiens [Pathway:R-HSA-5654719] SHC-mediated cascade:FGFR4 - Homo sapiens [Pathway:R-HSA-5654720] PI-3K cascade:FGFR4 - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2018-03-26
literatureReference	[LiteratureReference:191518] Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism
maxDepth	3
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Downstream signaling of activated FGFR4
orthologousEvent	[Pathway:R-CEL-5654716] Downstream signaling of activated FGFR4 - Caenorhabditis elegans [Pathway:R-DME-5654716] Downstream signaling of activated FGFR4 - Drosophila melanogaster [Pathway:R-GGA-5654716] Downstream signaling of activated FGFR4 - Gallus gallus [Pathway:R-XTR-5654716] Downstream signaling of activated FGFR4 - Xenopus tropicalis [Pathway:R-DRE-5654716] Downstream signaling of activated FGFR4 - Danio rerio [Pathway:R-SSC-5654716] Downstream signaling of activated FGFR4 - Sus scrofa [Pathway:R-BTA-5654716] Downstream signaling of activated FGFR4 - Bos taurus [Pathway:R-CFA-5654716] Downstream signaling of activated FGFR4 - Canis familiaris [Pathway:R-RNO-5654716] Downstream signaling of activated FGFR4 - Rattus norvegicus [Pathway:R-MMU-5654716] Downstream signaling of activated FGFR4 - Mus musculus
releaseDate	2010-03-16
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:192607] Mohammadi, M, 2007-02-06 21:44:35
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-5654716
summation	[Summation:191012] Signaling via FGFRs is mediated via direct recruitment of si...
updateTrackers	[UpdateTracker:9779769] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v64:[updateIndirectRLE] [UpdateTracker:9782612] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v59:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9782781] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v58:[updateContainedPathway] [UpdateTracker:9784830] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v53:[updateContainedPathway] [UpdateTracker:9783396] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v56:[updateContainedPathway]

Referrals

(updatedInstance)	[UpdateTracker:9779769] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v64:[updateIndirectRLE] [UpdateTracker:9782612] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v59:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9782781] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v58:[updateContainedPathway] [UpdateTracker:9784830] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v53:[updateContainedPathway] [UpdateTracker:9783396] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v56:[updateContainedPathway]
(replacementInstances)	[Deleted:5655585] Deletion of instance: 190333
(hasEvent)	[Pathway:R-HSA-5654743] Signaling by FGFR4

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