Reactome | DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]

Schema > Complex > Entries

DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-5653773] USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5653766] USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA - Homo sapiens
created	[InstanceEdit:5653758] Orlic-Milacic, Marija, 2014-12-01
dbId	5653761
displayName	DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]
hasComponent	[DefinedSet:R-HSA-5653659] DNA polymerase Y [nucleoplasm] [Complex:R-HSA-5653747] MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] [Complex:R-HSA-68436] RFC Heteropentamer [nucleoplasm] [Complex:R-HSA-68462] RPA heterotrimer [nucleoplasm] [DefinedSet:R-HSA-5653662] TLS-DNA Template [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Mus musculus [Complex:R-RNO-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Canis familiaris [Complex:R-BTA-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Bos taurus [Complex:R-SSC-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Sus scrofa [Complex:R-DRE-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Danio rerio [Complex:R-GGA-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Gallus gallus [Complex:R-DME-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Caenorhabditis elegans [Complex:R-SPO-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Schizosaccharomyces pombe
isChimeric	false
literatureReference	[LiteratureReference:5653648] Modification of PCNA by ISG15 plays a crucial role in termination of error-prone translesion DNA synthesis
maxDepth	5
name	DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template
producedByEvent	[Reaction:R-HSA-5653754] UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5653761
updateTrackers	[UpdateTracker:9893883] Update Tracker - [Complex:5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - v56:[updateContainedComponent] [UpdateTracker:9896994] Update Tracker - [Complex:5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - v61:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9893883] Update Tracker - [Complex:5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - v56:[updateContainedComponent] [UpdateTracker:9896994] Update Tracker - [Complex:5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - v61:[updateContainedComponent]
(output)	[Reaction:R-HSA-5653754] UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA
(hasComponent)	[Complex:R-HSA-5653773] USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]
(input)	[Reaction:R-HSA-5653766] USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA

© 2026 Reactome

Cite Us!