Reactome | REV1 recruits POLZ to (AP:Cyt)-DNA Template

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REV1 recruits POLZ to (AP:Cyt)-DNA Template Show undefined attributes

authored	[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5652143] Orlic-Milacic, Marija, 2014-11-28
dbId	5652151
deleted	[Deleted:5676179] Deletion of instance: 110321
displayName	REV1 recruits POLZ to (AP:Cyt)-DNA Template
edited	[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
eventOf	[Pathway:R-HSA-110312] Translesion synthesis by REV1 - Homo sapiens
followingEvent	[Reaction:R-HSA-110311] POLZ extends translesion synthesis - Homo sapiens
input	[Complex:R-HSA-110279] POLZ [nucleoplasm] [Complex:R-HSA-110285] REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5652030] Deoxycytidyl transferase activity of yeast REV1 protein [LiteratureReference:5652147] Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1 [LiteratureReference:5652156] Structural insights into the assembly of human translesion polymerase complexes [LiteratureReference:5652161] Structural basis of recruitment of DNA polymerase ? by interaction between REV1 and REV7 proteins
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	REV1 recruits POLZ to (AP:Cyt)-DNA Template
orthologousEvent	[Reaction:R-PFA-5652151] REV1 recruits POLZ to (AP:Cyt)-DNA Template - Plasmodium falciparum [Reaction:R-SPO-5652151] REV1 recruits POLZ to (AP:Cyt)-DNA Template - Schizosaccharomyces pombe [Reaction:R-DME-5652151] REV1 recruits POLZ to (AP:Cyt)-DNA Template - Drosophila melanogaster [Reaction:R-GGA-5652151] REV1 recruits POLZ to (AP:Cyt)-DNA Template - Gallus gallus [Reaction:R-SSC-5652151] REV1 recruits POLZ to (AP:Cyt)-DNA Template - Sus scrofa [Reaction:R-CFA-5652151] REV1 recruits POLZ to (AP:Cyt)-DNA Template - Canis familiaris [Reaction:R-RNO-5652151] REV1 recruits POLZ to (AP:Cyt)-DNA Template - Rattus norvegicus [Reaction:R-MMU-5652151] REV1 recruits POLZ to (AP:Cyt)-DNA Template - Mus musculus
output	[Complex:R-HSA-5652152] POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm]
precedingEvent	[Reaction:R-HSA-110308] REV1 inserts dCMP opposite to AP sites in DNA - Homo sapiens [Reaction:R-HSA-110322] Formation of Pol zeta complex - Homo sapiens
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5663080] Borowiec, James, 2015-01-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5652151
summation	[Summation:5652157] REV1, bound to the replication complex, recruits DNA polymer...

Referrals

(replacementInstances)	[Deleted:5676179] Deletion of instance: 110321
(precedingEvent)	[Reaction:R-HSA-110311] POLZ extends translesion synthesis
(hasEvent)	[Pathway:R-HSA-110312] Translesion synthesis by REV1