Reactome | NEIL2:5-OHU-dsDNA [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:5649688] DNA N-glycosylase activity of NEIL2:5-OHU-dsDNA [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-5649681] NEIL2 cleaves 5-OHU from damaged DNA - Homo sapiens
created	[InstanceEdit:5649680] Orlic-Milacic, Marija, 2014-11-20
dbId	5649682
displayName	NEIL2:5-OHU-dsDNA [nucleoplasm]
hasComponent	[GenomeEncodedEntity:R-HSA-110153] 5-OHU-dsDNA [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5649650] NEIL2 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-5649682] NEIL2:5-OHU-dsDNA [nucleoplasm] - Mus musculus [Complex:R-RNO-5649682] NEIL2:5-OHU-dsDNA [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-5649682] NEIL2:5-OHU-dsDNA [nucleoplasm] - Canis familiaris [Complex:R-BTA-5649682] NEIL2:5-OHU-dsDNA [nucleoplasm] - Bos taurus [Complex:R-SSC-5649682] NEIL2:5-OHU-dsDNA [nucleoplasm] - Sus scrofa [Complex:R-XTR-5649682] NEIL2:5-OHU-dsDNA [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-5649682] NEIL2:5-OHU-dsDNA [nucleoplasm] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:5649684] Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions
maxDepth	2
modified	[InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12
name	NEIL2:5-OHU-dsDNA
producedByEvent	[Reaction:R-HSA-5649686] NEIL2 recognizes and binds 5-OHU-dsDNA - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5649682

(output)	[Reaction:R-HSA-5649686] NEIL2 recognizes and binds 5-OHU-dsDNA
(input)	[Reaction:R-HSA-5649681] NEIL2 cleaves 5-OHU from damaged DNA
(physicalEntity)	[CatalystActivity:5649688] DNA N-glycosylase activity of NEIL2:5-OHU-dsDNA [nucleoplasm]