Reactome | Defective Mismatch Repair Associated With MSH3

Schema > Pathway > Entries

authored	[InstanceEdit:1981184] Gillespie, ME, 2011-11-09
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5632929] Gillespie, Marc E, 2014-10-29
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	5632927
disease	[Disease:1500689] cancer
displayName	Defective Mismatch Repair Associated With MSH3
edited	[InstanceEdit:8980077] Gillespie, Marc E, 2017-02-27
eventOf	[Pathway:R-HSA-5423599] Diseases of Mismatch Repair (MMR) - Homo sapiens
hasDiagram	true
hasEHLD	false
hasEvent	[FailedReaction:R-HSA-5578663] MSH3 variant:MSH2-defective DNA mismatch repair - Homo sapiens
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:5578670] Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair
maxDepth	2
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Defective Mismatch Repair Associated With MSH3
normalPathway	[Pathway:R-HSA-5358508] Mismatch Repair
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8944056] Arora, Sanjeevani, 2016-11-01
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-5632927
summation	[Summation:5633024] MSH3 forms a heterodimer with MSH2 to form the MSH3:MSH2 com...

(hasEvent)

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