Reactome | p-S939,T1462-TSC2:14-3-3 dimer [cytosol]

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p-S939,T1462-TSC2:14-3-3 dimer [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5632726] Orlic-Milacic, Marija, 2014-10-28
dbId	5632727
displayName	p-S939,T1462-TSC2:14-3-3 dimer [cytosol]
hasComponent	[DefinedSet:R-HSA-1445138] 14-3-3 dimer [cytosol] [EntityWithAccessionedSequence:R-HSA-199484] p-S939,T1462-TSC2 [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - Mus musculus [Complex:R-RNO-5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - Rattus norvegicus [Complex:R-CFA-5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - Canis familiaris [Complex:R-BTA-5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - Bos taurus [Complex:R-SSC-5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - Sus scrofa [Complex:R-XTR-5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - Xenopus tropicalis [Complex:R-GGA-5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - Gallus gallus [Complex:R-DME-5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - Drosophila melanogaster [Complex:R-DDI-5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - Dictyostelium discoideum [Complex:R-SPO-5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - Schizosaccharomyces pombe
isChimeric	false
literatureReference	[LiteratureReference:5632730] 14-3-3 interacts with the tumor suppressor tuberin at Akt phosphorylation site(s) [LiteratureReference:5632718] Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning
maxDepth	4
modified	[InstanceEdit:5632734] Orlic-Milacic, Marija, 2014-10-28
name	p-S939,T1462-TSC2:14-3-3 dimer
producedByEvent	[Reaction:R-HSA-5632732] p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5632727
updateTrackers	[UpdateTracker:9902616] Update Tracker - [Complex:5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - v78:[updateContainedComponent] [UpdateTracker:9899101] Update Tracker - [Complex:5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - v65:[updateContainedComponent] [UpdateTracker:9895249] Update Tracker - [Complex:5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - v59:[updateContainedComponent] [UpdateTracker:9899578] Update Tracker - [Complex:5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - v66:[updateContainedComponent]

Referrals

(updatedInstance)

(output)

[Reaction:R-HSA-5632732] p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4

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