Reactome | MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm]

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5617667] May, Bruce, 2014-08-13
dbId	5617651
displayName	MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-3782562] CTCF [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5617647] HOXA3 gene [nucleoplasm] [Complex:R-HSA-5617660] HOXB1:PBX1:PKNOX1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-3788667] MAFB [nucleoplasm] [DefinedSet:R-HSA-5619379] MLL3,4 complex [nucleoplasm] [Complex:R-HSA-1214169] Nucleosome with H3K4me3 [nucleoplasm] [Complex:R-HSA-209680] RNA Polymerase II holoenzyme complex (generic) [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-MMU-5619399] Mafb,Hoxb1:Pbx1:Pknox1 at active Hoxa3 chromatin [nucleoplasm] - Mus musculus
isChimeric	false
literatureReference	[LiteratureReference:5624425] CTCF Controls HOXA Cluster Silencing and Mediates PRC2-Repressive Higher-Order Chromatin Structure in NT2/D1 Cells
maxDepth	6
modified	[InstanceEdit:5690639] May, Bruce, 2015-04-30
name	MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin
positivelyRegulates	[PositiveGeneExpressionRegulation:R-HSA-5634092] Positive gene expression regulation by 'MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm]'
producedByEvent	[BlackBoxEvent:R-HSA-5617641] MAFB (KREISLER) and HOXB1:PBX1:PKNOX1 (HOXB1:PBX1:PREP1) activate HOXA3 expression - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5617651
updateTrackers	[UpdateTracker:9906577] Update Tracker - [Complex:5617651] MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm] - v87:[updateContainedComponent] [UpdateTracker:9904735] Update Tracker - [Complex:5617651] MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm] - v84:[updateContainedComponent] [UpdateTracker:9894387] Update Tracker - [Complex:5617651] MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm] - v57:[updateContainedComponent]

MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm] Show undefined attributes

Referrals

(updatedInstance)	[UpdateTracker:9906577] Update Tracker - [Complex:5617651] MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm] - v87:[updateContainedComponent] [UpdateTracker:9904735] Update Tracker - [Complex:5617651] MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm] - v84:[updateContainedComponent] [UpdateTracker:9894387] Update Tracker - [Complex:5617651] MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm] - v57:[updateContainedComponent]
(inferredTo)	[Complex:R-MMU-5619399] Mafb,Hoxb1:Pbx1:Pknox1 at active Hoxa3 chromatin [nucleoplasm]
(output)	[BlackBoxEvent:R-HSA-5617641] MAFB (KREISLER) and HOXB1:PBX1:PKNOX1 (HOXB1:PBX1:PREP1) activate HOXA3 expression
(regulator)	[PositiveGeneExpressionRegulation:R-HSA-5634092] Positive gene expression regulation by 'MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm]'