Reactome | HOXA2 bivalent chromatin [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[BlackBoxEvent:R-HSA-6810139] HOXA2 chromatin is activated - Homo sapiens
created	[InstanceEdit:5617500] May, Bruce, 2014-08-12
dbId	5617490
displayName	HOXA2 bivalent chromatin [nucleoplasm]
hasComponent	[Complex:R-HSA-5617447] Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5617497] HOXA2 gene [nucleoplasm] [Complex:R-HSA-212285] PRC2 (EZH2) Core [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-MMU-5619383] Hoxa2 bivalent chromatin [nucleoplasm] - Mus musculus
isChimeric	false
literatureReference	[LiteratureReference:5620950] Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster [LiteratureReference:4687095] Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination [LiteratureReference:5620939] Overlapping roles of the methylated DNA-binding protein MBD1 and polycomb group proteins in transcriptional repression of HOXA genes and heterochromatin foci formation
maxDepth	4
modified	[InstanceEdit:6810175] May, Bruce, 2015-11-16
name	HOXA2 bivalent chromatin
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5617490
updateTrackers	[UpdateTracker:9894575] Update Tracker - [Complex:5617490] HOXA2 bivalent chromatin [nucleoplasm] - v57:[updateContainedComponent] [UpdateTracker:9904731] Update Tracker - [Complex:5617490] HOXA2 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]

(updatedInstance)	[UpdateTracker:9894575] Update Tracker - [Complex:5617490] HOXA2 bivalent chromatin [nucleoplasm] - v57:[updateContainedComponent] [UpdateTracker:9904731] Update Tracker - [Complex:5617490] HOXA2 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
(inferredTo)	[Complex:R-MMU-5619383] Hoxa2 bivalent chromatin [nucleoplasm]
(input)	[BlackBoxEvent:R-HSA-6810139] HOXA2 chromatin is activated