Reactome | MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events

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MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events Show undefined attributes

authored	[InstanceEdit:5601882] May, Bruce, 2014-06-14
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:13231] nuclear envelope [Compartment:7660] nucleoplasm
created	[InstanceEdit:5601904] May, Bruce, 2014-06-15
dbId	5601897
displayName	MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events
edited	[InstanceEdit:5601882] May, Bruce, 2014-06-14
eventOf	[Pathway:R-HSA-5601884] PIWI-interacting RNA (piRNA) biogenesis - Homo sapiens
followingEvent	[Reaction:R-HSA-9727450] PIWIL4:piRNA binds nascent LINE1 pre-RNA and recruits SPOCD1, C19ORF84, DNMT3A, DNMT3L, the NURD complex, and the BAF complex - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-5606256] MeR-Piwil4:2'-O-methyl-piRNA:Tdrd9:Mael:Tdrkh dissociates and MeR-Piwil4:2'-O-methyl-piRNA, Tdrd9, Mael translocate from cytosol to nucleus in unknown association and unknown order of events - Mus musculus
input	[Complex:R-HSA-5603060] MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events PIWIL4:piRNA translocates from cytosol to nucleus
output	[EntityWithAccessionedSequence:R-HSA-5636062] MAEL [nucleoplasm] [Complex:R-HSA-5601885] MeR-PIWIL4:2'-O-methyl-piRNA [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5603057] TDRD9 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5608255] TDRKH [cytosol]
precedingEvent	[Reaction:R-HSA-5629237] HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH - Homo sapiens
releaseDate	2014-12-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5629251] Saito, Kuniaki, 2014-10-25
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-5601897
summation	[Summation:5603152] As inferred from homologs in mouse, PIWIL4 is loaded with pi...

Referrals

(precedingEvent)	[Reaction:R-HSA-9727450] PIWIL4:piRNA binds nascent LINE1 pre-RNA and recruits SPOCD1, C19ORF84, DNMT3A, DNMT3L, the NURD complex, and the BAF complex
(hasEvent)	[Pathway:R-HSA-5601884] PIWI-interacting RNA (piRNA) biogenesis
(inferredTo)	[BlackBoxEvent:R-MMU-5606256] MeR-Piwil4:2'-O-methyl-piRNA:Tdrd9:Mael:Tdrkh dissociates and MeR-Piwil4:2'-O-methyl-piRNA, Tdrd9, Mael translocate from cytosol to nucleus in unknown association and unknown order of events

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