Reactome | Defective MAOA causes BRUNS

Schema > Pathway > Entries

authored	[InstanceEdit:5579003] Jassal, Bijay, 2014-06-06
created	[InstanceEdit:5579003] Jassal, Bijay, 2014-06-06
dbId	5579012
disease	[Disease:5603074] disease of mental health
displayName	Defective MAOA causes BRUNS
edited	[InstanceEdit:5579003] Jassal, Bijay, 2014-06-06
eventOf	[Pathway:R-HSA-5579029] Metabolic disorders of biological oxidation enzymes - Homo sapiens
hasDiagram	true
hasEHLD	false
hasEvent	[FailedReaction:R-HSA-5603108] Defective MAOA does not oxidatively deaminate 5HT - Homo sapiens
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:379298] Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A [LiteratureReference:5603080] Role of MAO A and B in neurotransmitter metabolism and behavior [LiteratureReference:5618155] Cloning, after cloning, knock-out mice, and physiological functions of MAO A and B
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Defective MAOA causes BRUNS Defective MAOA causes Brunner syndrome (BRUNS)
normalPathway	[Pathway:R-HSA-211945] Phase I - Functionalization of compounds
releaseDate	2014-12-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5634119] Nakaki, Toshio, 2014-11-03
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-5579012
summation	[Summation:5603090] Amine oxidase (flavin-containing) A (MAOA) catalyses the oxi...

(hasEvent)

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