Reactome | Phase 3 - rapid repolarisation

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Phase 3 - rapid repolarisation Show undefined attributes

authored	[InstanceEdit:5576887] Jassal, Bijay, 2014-05-27 [InstanceEdit:9977629] Gesino, Anthony, 2025-08-19 [InstanceEdit:9977627] Vaglio, Arielle, 2025-08-19
created	[InstanceEdit:5576887] Jassal, Bijay, 2014-05-27
dbId	5576890
displayName	Phase 3 - rapid repolarisation
edited	[InstanceEdit:5576887] Jassal, Bijay, 2014-05-27
eventOf	[Pathway:R-HSA-5576891] Cardiac conduction - Homo sapiens
followingEvent	[Pathway:R-HSA-5576886] Phase 4 - resting membrane potential - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:1042616] cardiac conduction
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-5577050] AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region - Homo sapiens [Reaction:R-HSA-5577237] KCNH2:KCNE transport K+ from cytosol to extracellular region - Homo sapiens [Reaction:R-HSA-9613264] Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE - Homo sapiens [Reaction:R-HSA-9613570] Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2022-06-09
literatureReference	[LiteratureReference:5578914] Cardiac ion channels [LiteratureReference:5578909] The cardiac conduction system
maxDepth	2
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Phase 3 - rapid repolarisation
orthologousEvent	[Pathway:R-PFA-5576890] Phase 3 - rapid repolarisation - Plasmodium falciparum [Pathway:R-CEL-5576890] Phase 3 - rapid repolarisation - Caenorhabditis elegans [Pathway:R-DME-5576890] Phase 3 - rapid repolarisation - Drosophila melanogaster [Pathway:R-GGA-5576890] Phase 3 - rapid repolarisation - Gallus gallus [Pathway:R-XTR-5576890] Phase 3 - rapid repolarisation - Xenopus tropicalis [Pathway:R-SSC-5576890] Phase 3 - rapid repolarisation - Sus scrofa [Pathway:R-BTA-5576890] Phase 3 - rapid repolarisation - Bos taurus [Pathway:R-CFA-5576890] Phase 3 - rapid repolarisation - Canis familiaris [Pathway:R-RNO-5576890] Phase 3 - rapid repolarisation - Rattus norvegicus [Pathway:R-MMU-5576890] Phase 3 - rapid repolarisation - Mus musculus
precedingEvent	[Pathway:R-HSA-5576893] Phase 2 - plateau phase - Homo sapiens
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6809173] Colotti, Gianni, 2015-11-09
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-5576890
summation	[Summation:5578805] In phase 3 (the "rapid repolarisation" phase), the L-type Ca...
updateTrackers	[UpdateTracker:9777912] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v68:[updateContainedRLE] [UpdateTracker:9778854] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v67:[updateContainedRLE] [UpdateTracker:9774791] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v81:[addHasEvent] [UpdateTracker:9779229] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v66:[modifyText, updateContainedRLE] [UpdateTracker:9776485] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v75:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9777912] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v68:[updateContainedRLE] [UpdateTracker:9778854] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v67:[updateContainedRLE] [UpdateTracker:9774791] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v81:[addHasEvent] [UpdateTracker:9779229] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v66:[modifyText, updateContainedRLE] [UpdateTracker:9776485] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v75:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-5576891] Cardiac conduction
(precedingEvent)	[Pathway:R-HSA-5576886] Phase 4 - resting membrane potential

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