Reactome | Phase 3 - rapid repolarisation

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Phase 3 - rapid repolarisation Show undefined attributes

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10331159
displayName	Phase 3 - rapid repolarisation
eventOf	[Pathway:R-CFA-5576891] Cardiac conduction - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-CFA-5576886] Phase 4 - resting membrane potential - Canis familiaris
goBiologicalProcess	[GO_BiologicalProcess:1042616] cardiac conduction
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-5577237] KCNH2:KCNE transport K+ from cytosol to extracellular region - Canis familiaris [Reaction:R-CFA-9613264] Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE - Canis familiaris [Reaction:R-CFA-9613570] Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers - Canis familiaris
inferredFrom	[Pathway:R-HSA-5576890] Phase 3 - rapid repolarisation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Phase 3 - rapid repolarisation
precedingEvent	[Pathway:R-CFA-5576893] Phase 2 - plateau phase - Canis familiaris
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-5576890
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-5576891] Cardiac conduction
(precedingEvent)	[Pathway:R-CFA-5576886] Phase 4 - resting membrane potential
(inferredTo)	[Pathway:R-HSA-5576890] Phase 3 - rapid repolarisation

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