Reactome | ERCC6 [nucleoplasm]

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ERCC6 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-5365864] ERCC6 dimer [nucleoplasm] - Homo sapiens [Complex:R-HSA-5365864] ERCC6 dimer [nucleoplasm] - Homo sapiens [Complex:R-NUL-573330] Ttf-I:rDNA:CSB:G9a:NuRD [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782230] TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] - Homo sapiens [Complex:R-HSA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-6781840] ERCC6 binds stalled RNA Pol II - Homo sapiens [Reaction:R-NUL-573385] Recruitment of CSB, G9a, and NuRD to the rRNA promoter - Homo sapiens
dbId	54429
displayName	ERCC6 [nucleoplasm]
endCoordinate	1493
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-54429] ERCC6 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-54429] Ercc6 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-54429] ERCC6 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-54429] ERCC6 [nucleoplasm] - Bos taurus [GenomeEncodedEntity:R-SSC-54429] Ghost homologue of ERCC6 [nucleoplasm] - Sus scrofa [GenomeEncodedEntity:R-DRE-54429] Ghost homologue of ERCC6 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-54429] ercc6 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-54429] ERCC6 [nucleoplasm] - Gallus gallus [GenomeEncodedEntity:R-DME-54429] Ghost homologue of ERCC6 [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-54429] ERCC6 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-54429] ercc6 [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-54429] ERCC6 [nucleoplasm] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-54429] ERCC6 [nucleoplasm] - Saccharomyces cerevisiae [GenomeEncodedEntity:R-PFA-54429] Ghost homologue of ERCC6 [nucleoplasm] - Plasmodium falciparum
maxDepth	1
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	ERCC6 CSB protein Excision repair protein ERCC-6 (Cockayne syndrome protein CSB) DNA excision repair protein ERCC-6 Cockayne syndrome protein CSB
referenceEntity	[ReferenceGeneProduct:uniprot:Q03468] UniProt:Q03468 ERCC6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-54429
startCoordinate	1
updateTrackers	[UpdateTracker:9878958] Update Tracker - [EntityWithAccessionedSequence:54429] ERCC6 [nucleoplasm] - v44:[modifyEndCoordinate] [UpdateTracker:9881650] Update Tracker - [EntityWithAccessionedSequence:54429] ERCC6 [nucleoplasm] - v45:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9878958] Update Tracker - [EntityWithAccessionedSequence:54429] ERCC6 [nucleoplasm] - v44:[modifyEndCoordinate] [UpdateTracker:9881650] Update Tracker - [EntityWithAccessionedSequence:54429] ERCC6 [nucleoplasm] - v45:[addName]
(hasComponent)	[Complex:R-NUL-573330] Ttf-I:rDNA:CSB:G9a:NuRD [nucleoplasm] [Complex:R-HSA-5365864] ERCC6 dimer [nucleoplasm] [Complex:R-HSA-6782230] TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] [Complex:R-HSA-6782220] TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] [Complex:R-HSA-6782222] TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] [Complex:R-HSA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] [Complex:R-HSA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] [Complex:R-HSA-6782112] Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] [Complex:R-HSA-9684120] Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] [Complex:R-HSA-6782065] Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] [Complex:R-HSA-6781837] Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm]
(input)	[Reaction:R-NUL-573385] Recruitment of CSB, G9a, and NuRD to the rRNA promoter [Reaction:R-HSA-6781840] ERCC6 binds stalled RNA Pol II

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