Reactome | AFXBO hydrolyses non-enzymatically to AFBDHD

Schema > Reaction > Entries

authored	[InstanceEdit:5423628] Jassal, Bijay, 2014-05-09
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5423628] Jassal, Bijay, 2014-05-09
dbId	5423656
displayName	AFXBO hydrolyses non-enzymatically to AFBDHD
edited	[InstanceEdit:5423628] Jassal, Bijay, 2014-05-09
eventOf	[Pathway:R-HSA-5423646] Aflatoxin activation and detoxification - Homo sapiens
followingEvent	[Reaction:R-HSA-5423694] AFBDHD hydrolyses non-enzymatically to AFBDHO - Homo sapiens
input	[SimpleEntity:R-ALL-159211] AFXBO [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5423688] Aflatoxin B1 8,9-epoxide hydrolysis in the presence of rat and human epoxide hydrolase [LiteratureReference:5423658] Activation and detoxication of aflatoxin B1
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	AFXBO hydrolyses non-enzymatically to AFBDHD
output	[SimpleEntity:R-ALL-5423726] AFBDHD [cytosol]
precedingEvent	[Reaction:R-HSA-156526] CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO - Homo sapiens
releaseDate	2014-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5545505] D'Eustachio, Peter, 2014-05-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5423656
summation	[Summation:5423675] The exo- and endo-epoxides of aflatoxin B1 are unstable in w...

(hasEvent)	[Pathway:R-HSA-5423646] Aflatoxin activation and detoxification
(precedingEvent)	[Reaction:R-HSA-5423694] AFBDHD hydrolyses non-enzymatically to AFBDHO

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