Reactome | NIPAs transport Mg2+ from extracellular region to cytosol

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NIPAs transport Mg2+ from extracellular region to cytosol Show undefined attributes

authored	[InstanceEdit:5336462] Jassal, Bijay, 2014-03-03
catalystActivity	[CatalystActivity:5336445] magnesium ion transmembrane transporter activity of NIPAs [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:5336462] Jassal, Bijay, 2014-03-03
crossReference	[DatabaseIdentifier:12668187] RHEA:29827
dbId	5336453
displayName	NIPAs transport Mg2+ from extracellular region to cytosol
edited	[InstanceEdit:5336462] Jassal, Bijay, 2014-03-03
eventOf	[Pathway:R-HSA-5223345] Miscellaneous transport and binding events - Homo sapiens
input	[SimpleEntity:R-ALL-114632] Mg2+ [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5336431] NIPA1(SPG6), the basis for autosomal dominant form of hereditary spastic paraplegia, encodes a functional Mg2+ transporter
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	NIPAs transport Mg2+ from extracellular region to cytosol
orthologousEvent	[Reaction:R-PFA-5336453] NIPAs transport Mg2+ from extracellular region to cytosol - Plasmodium falciparum [Reaction:R-CEL-5336453] NIPAs transport Mg2+ from extracellular region to cytosol - Caenorhabditis elegans [Reaction:R-DME-5336453] NIPAs transport Mg2+ from extracellular region to cytosol - Drosophila melanogaster [Reaction:R-XTR-5336453] NIPAs transport Mg2+ from extracellular region to cytosol - Xenopus tropicalis [Reaction:R-DRE-5336453] NIPAs transport Mg2+ from extracellular region to cytosol - Danio rerio [Reaction:R-SSC-5336453] NIPAs transport Mg2+ from extracellular region to cytosol - Sus scrofa [Reaction:R-BTA-5336453] NIPAs transport Mg2+ from extracellular region to cytosol - Bos taurus [Reaction:R-CFA-5336453] NIPAs transport Mg2+ from extracellular region to cytosol - Canis familiaris [Reaction:R-RNO-5336453] NIPAs transport Mg2+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-MMU-5336453] NIPAs transport Mg2+ from extracellular region to cytosol - Mus musculus
output	[SimpleEntity:R-ALL-29926] Mg2+ [cytosol]
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5674208] D'Eustachio, Peter, 2015-02-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5336453
summation	[Summation:5336450] Magnesium (Mg2+) is required for the catalytic activity of n...

Referrals

(hasEvent)

[Pathway:R-HSA-5223345] Miscellaneous transport and binding events