Reactome | CPNEs bind PL

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CPNEs bind PL Show undefined attributes

authored	[InstanceEdit:5333641] Jassal, Bijay, 2014-02-20
catalystActivity	[CatalystActivity:9949549] protein-membrane adaptor activity of CPNEs [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5333641] Jassal, Bijay, 2014-02-20
dbId	5333678
displayName	CPNEs bind PL
edited	[InstanceEdit:5333641] Jassal, Bijay, 2014-02-20
eventOf	[Pathway:R-HSA-1483206] Glycerophospholipid biosynthesis - Homo sapiens
input	[DefinedSet:R-HSA-5333699] CPNEs [plasma membrane] [SimpleEntity:R-ALL-171142] PL [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5333717] Copines: a ubiquitous family of Ca(2+)-dependent phospholipid-binding proteins [LiteratureReference:5333648] The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	CPNEs bind PL Copines bind phospholipid
orthologousEvent	[Reaction:R-DDI-5333678] CPNEs bind PL - Dictyostelium discoideum [Reaction:R-GGA-5333678] CPNEs bind PL - Gallus gallus [Reaction:R-XTR-5333678] CPNEs bind PL - Xenopus tropicalis [Reaction:R-DRE-5333678] CPNEs bind PL - Danio rerio [Reaction:R-SSC-5333678] CPNEs bind PL - Sus scrofa [Reaction:R-BTA-5333678] CPNEs bind PL - Bos taurus [Reaction:R-CFA-5333678] CPNEs bind PL - Canis familiaris [Reaction:R-RNO-5333678] CPNEs bind PL - Rattus norvegicus [Reaction:R-MMU-5333678] CPNEs bind PL - Mus musculus
output	[Complex:R-HSA-5333679] CPNEs:PL [plasma membrane]
previousReviewStatus	[ReviewStatus:9821385] four stars
regulatedBy	[PositiveRegulation:R-HSA-5336148] Positive regulation by 'Ca2+ [cytosol]'
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5674208] D'Eustachio, Peter, 2015-02-11 [InstanceEdit:9962972] Hill, David P, 2025-08-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5333678
summation	[Summation:5333684] Copine 1, 3, 6 and 7 (CPNE1,3,6,7) are a family of calcium-d...
updateTrackers	[UpdateTracker:9953568] Update Tracker - [Reaction:5333678] CPNEs bind PL - v93:[removeCatalystActivity]

Referrals

(updatedInstance)	[UpdateTracker:9953568] Update Tracker - [Reaction:5333678] CPNEs bind PL - v93:[removeCatalystActivity]
(hasEvent)	[Pathway:R-HSA-1483206] Glycerophospholipid biosynthesis