Reactome | VAMP2(77-116) [synaptic vesicle membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:201753] synaptic vesicle membrane
created	[InstanceEdit:5228354] D'Eustachio, Peter, 2014-01-10
crossReference	[DatabaseIdentifier:12020820] Mondo:0005498
dbId	5228355
disease	[Disease:5228387] tetanus [Disease:3632909] botulism
displayName	VAMP2(77-116) [synaptic vesicle membrane]
endCoordinate	116
inDisease	true
literatureReference	[LiteratureReference:181771] Differences in the protease activities of tetanus and botulinum B toxins revealed by the cleavage of vesicle-associated membrane protein and various sized fragments [LiteratureReference:5228352] Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin
maxDepth	1
modified	[InstanceEdit:5246515] D'Eustachio, Peter, 2014-01-21
name	VAMP2(77-116) VAMP2 C-terminal fragment
producedByEvent	[Reaction:R-HSA-194796] botB LC cleaves target cell VAMP2 - Homo sapiens [Reaction:R-HSA-5228578] tetX LC cleaves target cell VAMP2 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P63027] UniProt:P63027 VAMP2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-5228355
startCoordinate	77

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