Reactome | B3GALTL transfers glucose to O-fucosyl-proteins

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B3GALTL transfers glucose to O-fucosyl-proteins Show undefined attributes

authored	[InstanceEdit:5172998] Jassal, B, 2013-11-25
catalystActivity	[CatalystActivity:5173109] glycosyltransferase activity of B3GLTC [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:5172998] Jassal, B, 2013-11-25
dbId	5173005
diseaseReaction	[FailedReaction:R-HSA-6785565] Defective B3GALTL does not transfer glucose to O-fucosyl-proteins - Homo sapiens
displayName	B3GALTL transfers glucose to O-fucosyl-proteins
edited	[InstanceEdit:5172998] Jassal, B, 2013-11-25
eventOf	[Pathway:R-HSA-5173214] O-glycosylation of TSR domain-containing proteins - Homo sapiens
input	[CandidateSet:R-HSA-5173164] O-fuc-proteins [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-173594] UDP-Glc [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6785563] Novel B3GALTL mutation in Peters-plus Syndrome [LiteratureReference:8849758] Peters plus syndrome mutations disrupt a noncanonical ER quality-control mechanism [LiteratureReference:8849773] Novel B3GALTL mutations in classic Peters plus syndrome and lack of mutations in a large cohort of patients with similar phenotypes
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	B3GALTL transfers glucose to O-fucosyl-proteins
orthologousEvent	[Reaction:R-CEL-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Caenorhabditis elegans [Reaction:R-DME-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Drosophila melanogaster [Reaction:R-GGA-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Gallus gallus [Reaction:R-XTR-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Xenopus tropicalis [Reaction:R-DRE-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Danio rerio [Reaction:R-SSC-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Sus scrofa [Reaction:R-BTA-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Bos taurus [Reaction:R-CFA-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Canis familiaris [Reaction:R-RNO-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Rattus norvegicus [Reaction:R-MMU-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Mus musculus
output	[CandidateSet:R-HSA-5173276] glc-fuc-proteins [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-158602] UDP [endoplasmic reticulum lumen]
precedingEvent	[Reaction:R-HSA-5173192] POFUT2 transfers fucose to TSR domain-containing proteins - Homo sapiens
releaseDate	2014-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5260211] D'Eustachio, Peter, 2014-02-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5173005
summation	[Summation:5187393] Human beta-1,3-glucosyltransferase-like protein (B3GALTL, HG...
updateTrackers	[UpdateTracker:9784123] Update Tracker - [Reaction:5173005] B3GALTL transfers glucose to O-fucosyl-proteins - v54:[addInput, addOutput, modifyText] [UpdateTracker:9783630] Update Tracker - [Reaction:5173005] B3GALTL transfers glucose to O-fucosyl-proteins - v56:[add_removeLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9784123] Update Tracker - [Reaction:5173005] B3GALTL transfers glucose to O-fucosyl-proteins - v54:[addInput, addOutput, modifyText] [UpdateTracker:9783630] Update Tracker - [Reaction:5173005] B3GALTL transfers glucose to O-fucosyl-proteins - v56:[add_removeLiteratureReference, modifyText]
(normalReaction)	[FailedReaction:R-HSA-6785565] Defective B3GALTL does not transfer glucose to O-fucosyl-proteins
(hasEvent)	[Pathway:R-HSA-5173214] O-glycosylation of TSR domain-containing proteins

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