Reactome | Aquaporins passively transport urea into cells

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Aquaporins passively transport urea into cells Show undefined attributes

authored	[InstanceEdit:507886] May, B, 2010-02-09
catalystActivity	[CatalystActivity:507887] urea channel activity of AQP9,10 [plasma membrane]
catalystActivityReference	[CatalystActivityReference:9643543] urea channel activity of AQP9,10 [plasma membrane] Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:507878] May, B, 2010-02-09
crossReference	[DatabaseIdentifier:12668143] RHEA:32799
dbId	507875
displayName	Aquaporins passively transport urea into cells
edited	[InstanceEdit:507886] May, B, 2010-02-09
eventOf	[Pathway:R-HSA-432047] Passive transport by Aquaporins - Homo sapiens
input	[SimpleEntity:R-ALL-432019] Urea [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:431678] Altered aquaporin 9 expression and localization in human hepatocellular carcinoma [LiteratureReference:431832] Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin [LiteratureReference:431837] Cloning of a new aquaporin (AQP10) abundantly expressed in duodenum and jejunum [LiteratureReference:431853] Compartmentalization of aquaporins in the human intestine [LiteratureReference:431908] Functional and molecular characterization of the human neutral solute channel aquaporin-9 [LiteratureReference:431916] Functional characterization of human aquaporin 9 as a facilitative glycerol carrier [LiteratureReference:431939] Immunolocalization of AQP9 in liver, epididymis, testis, spleen, and brain
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Aquaporins passively transport urea into cells
orthologousEvent	[Reaction:R-PFA-507875] Aquaporins passively transport urea into cells - Plasmodium falciparum [Reaction:R-SCE-507875] Aquaporins passively transport urea into cells - Saccharomyces cerevisiae [Reaction:R-SPO-507875] Aquaporins passively transport urea into cells - Schizosaccharomyces pombe [Reaction:R-CEL-507875] Aquaporins passively transport urea into cells - Caenorhabditis elegans [Reaction:R-GGA-507875] Aquaporins passively transport urea into cells - Gallus gallus [Reaction:R-XTR-507875] Aquaporins passively transport urea into cells - Xenopus tropicalis [Reaction:R-DRE-507875] Aquaporins passively transport urea into cells - Danio rerio [Reaction:R-SSC-507875] Aquaporins passively transport urea into cells - Sus scrofa [Reaction:R-BTA-507875] Aquaporins passively transport urea into cells - Bos taurus [Reaction:R-CFA-507875] Aquaporins passively transport urea into cells - Canis familiaris [Reaction:R-RNO-507875] Aquaporins passively transport urea into cells - Rattus norvegicus [Reaction:R-MMU-507875] Aquaporins passively transport urea into cells - Mus musculus
output	[SimpleEntity:R-ALL-29514] Urea [cytosol]
releaseDate	2009-06-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:879857] Beitz, E, 2010-06-24 [InstanceEdit:913479] Calamita, G, 2010-07-15 [InstanceEdit:918100] Mathai, JC, MacIver, B, 2010-07-31
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-507875
summation	[Summation:507879] Aquaporin-9 (AQP9) and AQP10 are 6-pass transmembrane protei...

Referrals

(hasEvent)	[Pathway:R-HSA-432047] Passive transport by Aquaporins
(reverseReaction)	[Reaction:R-HSA-507873] Aquaporins passively transport urea out of cells

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