Reactome | Negative gene expression regulation by 'EP400:p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm]'

Schema > NegativeGeneExpressionRegulation > Entries

activeUnit	[EntityWithAccessionedSequence:R-HSA-3321987] EP400 [nucleoplasm] - Homo sapiens
created	[InstanceEdit:4647599] Orlic-Milacic, M, 2013-09-30
dbId	4647597
displayName	Negative gene expression regulation by 'EP400:p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm]'
modified	[InstanceEdit:9608020] Wu, G, 2018-05-08
regulatedEntity	[BlackBoxEvent:R-HSA-4647613] Transcriptional activation of CDKN1A by TP53 is inhibited by EP400 - Homo sapiens
regulator	[Complex:R-HSA-4647605] EP400:p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm]
schemaClass	NegativeGeneExpressionRegulation
stId	R-HSA-4647597

(regulation)	[RegulationReference:9642410] Negative gene expression regulation by 'EP400:p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm]' The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway
(regulatedBy)	[BlackBoxEvent:R-HSA-4647613] Transcriptional activation of CDKN1A by TP53 is inhibited by EP400

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