Reactome | N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane]

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N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-4641177] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] - Homo sapiens
consumedByEvent	[FailedReaction:R-HSA-5340587] RNF43 frameshift mutants show enhanced WNT siganling - Homo sapiens [Reaction:R-HSA-4641249] ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex - Homo sapiens
created	[InstanceEdit:4641175] Rothfels, K, 2013-09-27
dbId	4641176
displayName	N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane]
hasComponent	[CandidateSet:R-HSA-4641164] FZD [plasma membrane] [CandidateSet:R-HSA-201719] LRP5/6 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-3247784] N4GlycoAsn-PalmS WNT3A [extracellular region]
inDisease	false
includedLocation	[Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-4641176] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] - Mus musculus [Complex:R-RNO-4641176] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-4641176] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] - Canis familiaris [Complex:R-BTA-4641176] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] - Bos taurus [Complex:R-SSC-4641176] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] - Sus scrofa [Complex:R-DRE-4641176] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] - Danio rerio [Complex:R-XTR-4641176] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-4641176] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] - Gallus gallus [Complex:R-CEL-4641176] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] - Caenorhabditis elegans
isChimeric	false
modified	[InstanceEdit:5334058] Rothfels, K, 2014-02-21
name	N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6
producedByEvent	[Reaction:R-HSA-4641236] USP8 deubiquitinates FZD to potentiate WNT signaling - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-4641176

Referrals

(input)	[FailedReaction:R-HSA-5340587] RNF43 frameshift mutants show enhanced WNT siganling [Reaction:R-HSA-4641249] ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex
(hasComponent)	[Complex:R-HSA-4641177] N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane]
(output)	[Reaction:R-HSA-4641236] USP8 deubiquitinates FZD to potentiate WNT signaling

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