Reactome | PIAS1 SUMOylates SATB2 with SUMO3

Schema > Reaction > Entries

PIAS1 SUMOylates SATB2 with SUMO3 Show undefined attributes

authored	[InstanceEdit:4570563] May, B, 2013-09-21
catalystActivity	[CatalystActivity:3247478] SUMO transferase activity of PIAS1 [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9643901] SUMO transferase activity of PIAS1 [nucleoplasm] Transcription factor Sp3 is silenced through SUMO modification by PIAS1
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:4615844] May, B, 2013-09-27
dbId	4615900
displayName	PIAS1 SUMOylates SATB2 with SUMO3
edited	[InstanceEdit:4570563] May, B, 2013-09-21 [InstanceEdit:8955403] Thibault, Pierre, 2017-01-11
eventOf	[Pathway:R-HSA-4551638] SUMOylation of chromatin organization proteins - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-4615944] SATB2 [nucleoplasm] 4 × [Complex:R-HSA-2993782] SUMO3:UBE2I [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:4616024] SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression [LiteratureReference:5627511] Targeted identification of SUMOylation sites in human proteins using affinity enrichment and paralog-specific reporter ions [LiteratureReference:8955404] Large-scale analysis of lysine SUMOylation by SUMO remnant immunoaffinity profiling
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	PIAS1 SUMOylates SATB2 with SUMO3
orthologousEvent	[Reaction:R-DME-4615900] PIAS1 SUMOylates SATB2 with SUMO3 - Drosophila melanogaster [Reaction:R-XTR-4615900] PIAS1 SUMOylates SATB2 with SUMO3 - Xenopus tropicalis [Reaction:R-SSC-4615900] PIAS1 SUMOylates SATB2 with SUMO3 - Sus scrofa [Reaction:R-BTA-4615900] PIAS1 SUMOylates SATB2 with SUMO3 - Bos taurus [Reaction:R-RNO-4615900] PIAS1 SUMOylates SATB2 with SUMO3 - Rattus norvegicus [Reaction:R-MMU-4615900] PIAS1 SUMOylates SATB2 with SUMO3 - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-4615865] polySUMO3-K233,K350-SATB2 [nucleoplasm] 4 × [EntityWithAccessionedSequence:R-HSA-912481] UBE2I [nucleoplasm]
precedingEvent	[Reaction:R-HSA-2993769] Transfer of SUMO3 from E1 to UBE2I (UBC9) - Homo sapiens
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8955403] Thibault, Pierre, 2017-01-11 [InstanceEdit:8956382] Lu, Jian, 2017-01-22 [InstanceEdit:8956359] Matunis, Michael J, 2017-01-22 [InstanceEdit:8956371] Yang, Wei-Chih, 2017-01-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-4615900
summation	[Summation:4615866] PIAS1 SUMOylates SATB2 at lysine-233 and lysine-350 with SUM...

Referrals

(hasEvent)

[Pathway:R-HSA-4551638] SUMOylation of chromatin organization proteins