Reactome | WNT5A:FZD [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:4608827] Rothfels, K, 2013-09-23
dbId	4608830
displayName	WNT5A:FZD [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-3247777] N4GlycoAsn-PalmS WNT5A(36-380) [extracellular region] [CandidateSet:R-HSA-5140744] WNT5A-binding FZDs [plasma membrane]
inDisease	false
includedLocation	[Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-4608830] WNT5A:FZD [plasma membrane] - Mus musculus [Complex:R-RNO-4608830] WNT5A:FZD [plasma membrane] - Rattus norvegicus [Complex:R-CFA-4608830] WNT5A:FZD [plasma membrane] - Canis familiaris [Complex:R-BTA-4608830] WNT5A:FZD [plasma membrane] - Bos taurus [Complex:R-SSC-4608830] WNT5A:FZD [plasma membrane] - Sus scrofa [Complex:R-DRE-4608830] WNT5A:FZD [plasma membrane] - Danio rerio [Complex:R-XTR-4608830] WNT5A:FZD [plasma membrane] - Xenopus tropicalis [Complex:R-DME-4608830] WNT5A:FZD [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-4608830] WNT5A:FZD [plasma membrane] - Caenorhabditis elegans
isChimeric	false
isRequired	[Requirement:R-HSA-5099882] Requirement by 'WNT5A:FZD [plasma membrane]'
modified	[InstanceEdit:8942281] Rothfels, Karen, 2016-10-11
name	WNT5A:FZD
positivelyRegulates	[Requirement:R-HSA-5099882] Requirement by 'WNT5A:FZD [plasma membrane]'
producedByEvent	[Reaction:R-HSA-5099886] WNT5A binding to FZD promotes PRICKLE1 degradation - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-4608830

(output)	[Reaction:R-HSA-5099886] WNT5A binding to FZD promotes PRICKLE1 degradation
(regulator)	[Requirement:R-HSA-5099882] Requirement by 'WNT5A:FZD [plasma membrane]'