Reactome | IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane]

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IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:507928] protein tyrosine kinase activity of IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-508438] IL2:IL2R trimer:p-JAK1:JAK3:p-SYK [plasma membrane] - Homo sapiens [Complex:R-HSA-508449] IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-508292] SYK binds IL2RB - Homo sapiens [Reaction:R-HSA-452122] JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB - Homo sapiens
created	[InstanceEdit:451938] Jupe, S, 2010-01-14
dbId	451920
displayName	IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane]
hasComponent	[Complex:R-HSA-451939] IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] [Complex:R-HSA-451911] IL2RG:JAK3 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] - Mus musculus [Complex:R-RNO-451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] - Canis familiaris [Complex:R-BTA-451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] - Bos taurus [Complex:R-SSC-451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] - Sus scrofa
isChimeric	false
maxDepth	5
name	IL2:IL2R trimer:p-JAK1:JAK3
producedByEvent	[Reaction:R-HSA-451942] Within the IL-2R complex JAK3 phosphorylates JAK1 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-451920
updateTrackers	[UpdateTracker:9871005] Update Tracker - [Complex:451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] - v39:[updateContainedComponent] [UpdateTracker:9872426] Update Tracker - [Complex:451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] - v41:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9871005] Update Tracker - [Complex:451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] - v39:[updateContainedComponent] [UpdateTracker:9872426] Update Tracker - [Complex:451920] IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] - v41:[updateContainedComponent]
(hasComponent)	[Complex:R-HSA-508438] IL2:IL2R trimer:p-JAK1:JAK3:p-SYK [plasma membrane] [Complex:R-HSA-508449] IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane]
(input)	[Reaction:R-HSA-508292] SYK binds IL2RB [Reaction:R-HSA-452122] JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB
(output)	[Reaction:R-HSA-451942] Within the IL-2R complex JAK3 phosphorylates JAK1
(physicalEntity)	[CatalystActivity:507928] protein tyrosine kinase activity of IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane]

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