Reactome | Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol]

Schema > Complex > Entries

Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[BlackBoxEvent:R-HSA-450466] AUF1:mRNA complex is degraded - Homo sapiens
created	[InstanceEdit:450588] May, B, 2009-12-16
dbId	450458
displayName	Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol]
hasComponent	[OtherEntity:R-ALL-450444] mRNA Transcript Targeted by AUF1(hnRNP D0) [cytosol] [Complex:R-HSA-450417] Ubiquitinated AUF1 Tetramer [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Mus musculus [Complex:R-RNO-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Rattus norvegicus [Complex:R-CFA-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Canis familiaris [Complex:R-BTA-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Bos taurus [Complex:R-SSC-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Sus scrofa [Complex:R-DRE-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Danio rerio [Complex:R-XTR-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Xenopus tropicalis [Complex:R-GGA-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Gallus gallus [Complex:R-DME-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Drosophila melanogaster [Complex:R-DDI-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Dictyostelium discoideum [Complex:R-PFA-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol] - Plasmodium falciparum
isChimeric	false
literatureReference	[LiteratureReference:450615] Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1 [LiteratureReference:450572] Alternate exon insertion controls selective ubiquitination and degradation of different AUF1 protein isoforms [LiteratureReference:450367] Assembly of AUF1 oligomers on U-rich RNA targets by sequential dimer association [LiteratureReference:450421] Control of mRNA decay by heat shock-ubiquitin-proteasome pathway [LiteratureReference:450528] Ubiquitin-dependent mechanism regulates rapid turnover of AU-rich cytokine mRNAs
maxDepth	4
name	Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex
producedByEvent	[BlackBoxEvent:R-HSA-450580] AUF1 (hnRNP D0) is ubiquitinylated - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-450458

Referrals

(input)	[BlackBoxEvent:R-HSA-450466] AUF1:mRNA complex is degraded
(output)	[BlackBoxEvent:R-HSA-450580] AUF1 (hnRNP D0) is ubiquitinylated

© 2026 Reactome

Cite Us!