Reactome | K63polyUb-TRAF6 [endosome membrane]

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K63polyUb-TRAF6 [endosome membrane] Show undefined attributes

compartment	[Compartment:74700] endosome membrane
componentOf	[Complex:R-HSA-975164] p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] - Homo sapiens [Complex:R-HSA-975164] p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] - Homo sapiens [Complex:R-HSA-975164] p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] - Homo sapiens [Complex:R-HSA-450309] viral dsRNA:TLR3:TICAM1:K63pUb-TRAF6 [endosome membrane] - Homo sapiens
created	[InstanceEdit:450323] Shamovsky, V, 2009-12-16
dbId	450227
displayName	K63polyUb-TRAF6 [endosome membrane]
endCoordinate	522
hasModifiedResidue	[GroupModifiedResidue:3080580] ubiquitinylated lysine (K63polyUb [endosome membrane]) at 124
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-450227] Traf6 [endosome membrane] - Mus musculus [EntityWithAccessionedSequence:R-RNO-450227] Traf6 [endosome membrane] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-450227] TRAF6 [endosome membrane] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-450227] TRAF6 [endosome membrane] - Bos taurus [EntityWithAccessionedSequence:R-SSC-450227] TRAF6 [endosome membrane] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-450227] K63polyUb-TRAF6 [endosome membrane] - Danio rerio [EntityWithAccessionedSequence:R-XTR-450227] traf6 [endosome membrane] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-450227] TRAF6 [endosome membrane] - Gallus gallus [EntityWithAccessionedSequence:R-DME-450227] Traf6 [endosome membrane] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DDI-450227] zfaA [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-2] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-3] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-4] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-5] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-6] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-7] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-8] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-9] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-10] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-11] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-12] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-13] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-14] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-15] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-16] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-17] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-18] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-19] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-20] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-21] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-22] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-23] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-450227-24] K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum [DefinedSet:R-DDI-450227-25] Homologues of K63polyUb-TRAF6 [endosome membrane] - Dictyostelium discoideum
literatureReference	[LiteratureReference:202511] Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation
maxDepth	1
modified	[InstanceEdit:3080581] D'Eustachio, P, 2013-02-07
name	K63polyUb-TRAF6 K63-linked-polyUb-TRAF6
referenceEntity	[ReferenceGeneProduct:uniprot:Q9Y4K3] UniProt:Q9Y4K3 TRAF6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-450227
startCoordinate	1

Referrals

(hasComponent)	[Complex:R-HSA-975164] p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] [Complex:R-HSA-450309] viral dsRNA:TLR3:TICAM1:K63pUb-TRAF6 [endosome membrane]
(activeUnit)	[CatalystActivity:8947977] ubiquitin-protein transferase activity of p-IRAK2:K63-linked pUb oligo-TRAF6 [plasma membrane]

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