Reactome | PROT mediates L-proline uptake

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PROT mediates L-proline uptake Show undefined attributes

authored	[InstanceEdit:444106] Jassal, Bijay, 2009-10-22
catalystActivity	[CatalystActivity:444116] proline:sodium symporter activity of SLC6A7 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:444106] Jassal, Bijay, 2009-10-22
dbId	444100
displayName	PROT mediates L-proline uptake
edited	[InstanceEdit:433105] Jassal, Bijay, 2009-08-21
eventOf	[Pathway:R-HSA-442660] SLC-mediated transport of neurotransmitters - Homo sapiens
input	[SimpleEntity:R-ALL-188972] Cl- [extracellular region] [SimpleEntity:R-ALL-352033] L-Pro [extracellular region] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:444122] Human brain-specific L-proline transporter: molecular cloning, functional expression, and chromosomal localization of the gene in human and mouse genomes
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	PROT mediates L-proline uptake
orthologousEvent	[Reaction:R-PFA-444100] PROT mediates L-proline uptake - Plasmodium falciparum [Reaction:R-CEL-444100] PROT mediates L-proline uptake - Caenorhabditis elegans [Reaction:R-DME-444100] PROT mediates L-proline uptake - Drosophila melanogaster [Reaction:R-GGA-444100] PROT mediates L-proline uptake - Gallus gallus [Reaction:R-XTR-444100] PROT mediates L-proline uptake - Xenopus tropicalis [Reaction:R-SSC-444100] PROT mediates L-proline uptake - Sus scrofa [Reaction:R-BTA-444100] PROT mediates L-proline uptake - Bos taurus [Reaction:R-CFA-444100] PROT mediates L-proline uptake - Canis familiaris [Reaction:R-RNO-444100] PROT mediates L-proline uptake - Rattus norvegicus [Reaction:R-MMU-444100] PROT mediates L-proline uptake - Mus musculus
output	[SimpleEntity:R-ALL-352022] Cl- [cytosol] [SimpleEntity:R-ALL-113538] L-Pro [cytosol] [SimpleEntity:R-ALL-83910] Na+ [cytosol]
releaseDate	2009-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:446289] He, Lei, 2009-11-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-444100
summation	[Summation:444142] The amino acid L-proline can act as a neurotransmitter. Its ...

Referrals

(hasEvent)

[Pathway:R-HSA-442660] SLC-mediated transport of neurotransmitters