Reactome | KLF4 [nucleoplasm]

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9793550] KLF4:CDH1 gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-480463] POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9765326] KLF4 binds CDH1 gene promoter - Homo sapiens [Reaction:R-HSA-480204] POU5F1 (OCT4), SOX2, NANOG, KLF4, PBX1, SMAD2 bind the NANOG promoter - Homo sapiens
created	[InstanceEdit:434461] May, B, 2009-08-29
dbId	434463
displayName	KLF4 [nucleoplasm]
endCoordinate	513
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-434463] Klf4 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-434463] KLF4 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-434463] KLF4 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-434463] KLF4 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-434463] KLF4 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-434463] klf4 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-434463] klf4 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-434463] KLF4 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-SCE-434463] CRZ1 [nucleoplasm] - Saccharomyces cerevisiae
maxDepth	1
modified	[InstanceEdit:3448660] Wu, G, 2013-05-16
name	KLF4 Krueppel-like factor 4 KLF4_HUMAN
positivelyRegulates	[PositiveGeneExpressionRegulation:R-HSA-977399] Positive gene expression regulation by 'KLF4 [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-434462] Positive gene expression regulation by 'KLF4 [nucleoplasm]'
producedByEvent	[BlackBoxEvent:R-HSA-9625409] KLF4 gene expression is stimulated by FOXO1,FOXO3 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:O43474] UniProt:O43474 KLF4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-434463
startCoordinate	1

(regulator)	[PositiveGeneExpressionRegulation:R-HSA-977399] Positive gene expression regulation by 'KLF4 [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-434462] Positive gene expression regulation by 'KLF4 [nucleoplasm]'
(output)	[BlackBoxEvent:R-HSA-9625409] KLF4 gene expression is stimulated by FOXO1,FOXO3
(input)	[Reaction:R-HSA-9765326] KLF4 binds CDH1 gene promoter [Reaction:R-HSA-480204] POU5F1 (OCT4), SOX2, NANOG, KLF4, PBX1, SMAD2 bind the NANOG promoter
(hasComponent)	[Complex:R-HSA-9793550] KLF4:CDH1 gene [nucleoplasm] [Complex:R-HSA-480463] POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm]
(activeUnit)	[PositiveGeneExpressionRegulation:9793578] Positive gene expression regulation by 'KLF4:CDH1 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5638456] Positive gene expression regulation by 'POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm]'

KLF4 [nucleoplasm] Show undefined attributes

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