Reactome | SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol

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SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol Show undefined attributes

authored	[InstanceEdit:433709] Jassal, Bijay, 2009-08-25
catalystActivity	[CatalystActivity:434169] monocarboxylic acid transmembrane transporter activity of SLC16A7:EMB,SLC16A3,8:BSG [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:433709] Jassal, Bijay, 2009-08-25
crossReference	[DatabaseIdentifier:11880510] Rhea:71775 [DatabaseIdentifier:11880589] Rhea:29415 [DatabaseIdentifier:11881043] Rhea:64720
dbId	433698
displayName	SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol
edited	[InstanceEdit:433105] Jassal, Bijay, 2009-08-21
eventOf	[Pathway:R-HSA-433692] Proton-coupled monocarboxylate transport - Homo sapiens
input	[SimpleEntity:R-ALL-351626] H+ [extracellular region] [DefinedSet:R-ALL-433683] MCT substrates [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:373885] Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter [LiteratureReference:433697] Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2 [LiteratureReference:445737] Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells [LiteratureReference:8959772] Monocarboxylic acid transport
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol MCTs mediate proton-coupled transport of monocarboxylates and ketone bodies
orthologousEvent	[Reaction:R-CEL-433698] SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol - Caenorhabditis elegans [Reaction:R-DME-433698] SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol - Drosophila melanogaster [Reaction:R-GGA-433698] SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol - Gallus gallus [Reaction:R-DRE-433698] SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol - Danio rerio [Reaction:R-SSC-433698] SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol - Sus scrofa [Reaction:R-BTA-433698] SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol - Bos taurus [Reaction:R-CFA-433698] SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol - Canis familiaris [Reaction:R-RNO-433698] SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-MMU-433698] SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol - Mus musculus
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [DefinedSet:R-ALL-433686] MCT substrates [cytosol]
releaseDate	2009-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:446289] He, Lei, 2009-11-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-433698
summation	[Summation:433700] Four members of the SLC16A gene family encode classical mono...

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(hasEvent)

[Pathway:R-HSA-433692] Proton-coupled monocarboxylate transport