Reactome | Gq activation by TP receptor

Schema > Reaction > Entries

Gq activation by TP receptor Show undefined attributes

authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
catalystActivity	[CatalystActivity:432080] guanyl-nucleotide exchange factor activity of TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:428751] Jupe, S, 2009-07-09
dbId	428750
displayName	Gq activation by TP receptor
edited	[InstanceEdit:445674] Jupe, S, 2009-11-03
eventOf	[Pathway:R-HSA-428930] Thromboxane signalling through TP receptor - Homo sapiens
followingEvent	[Reaction:R-HSA-428752] Dissociation of the TP:Gq complex - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-HSA-428764] TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:416867] The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Gq activation by TP receptor
orthologousEvent	[Reaction:R-CEL-428750] Gq activation by TP receptor - Caenorhabditis elegans [Reaction:R-DME-428750] Gq activation by TP receptor - Drosophila melanogaster [Reaction:R-GGA-428750] Gq activation by TP receptor - Gallus gallus [Reaction:R-XTR-428750] Gq activation by TP receptor - Xenopus tropicalis [Reaction:R-DRE-428750] Gq activation by TP receptor - Danio rerio [Reaction:R-SSC-428750] Gq activation by TP receptor - Sus scrofa [Reaction:R-BTA-428750] Gq activation by TP receptor - Bos taurus [Reaction:R-CFA-428750] Gq activation by TP receptor - Canis familiaris [Reaction:R-RNO-428750] Gq activation by TP receptor - Rattus norvegicus [Reaction:R-MMU-428750] Gq activation by TP receptor - Mus musculus
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-HSA-428904] TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane]
precedingEvent	[Reaction:R-HSA-428749] Activated TP receptor binds G-proten Gq - Homo sapiens
releaseDate	2009-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:445668] Poole, AW, 2009-11-02 [InstanceEdit:445653] Jones, ML, 2009-11-02 [InstanceEdit:445649] Harper, MT, 2009-11-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-428750
summation	[Summation:391991] The G-protein alpha subunit exchanges GDP for GTP

Referrals

(hasEvent)	[Pathway:R-HSA-428930] Thromboxane signalling through TP receptor
(precedingEvent)	[Reaction:R-HSA-428752] Dissociation of the TP:Gq complex