Reactome | Na+/H+ exchanger transport (at cell membrane)

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Na+/H+ exchanger transport (at cell membrane) Show undefined attributes

authored	[InstanceEdit:425976] Jassal, Bijay, 2009-06-11
catalystActivity	[CatalystActivity:425966] sodium:proton antiporter activity of SLC9A1-5 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:425976] Jassal, Bijay, 2009-06-11
crossReference	[DatabaseIdentifier:12668188] RHEA:29419 [DatabaseIdentifier:9958514] RHEA:29421
dbId	425994
displayName	Na+/H+ exchanger transport (at cell membrane)
edited	[InstanceEdit:425976] Jassal, Bijay, 2009-06-11
eventOf	[Pathway:R-HSA-425986] Sodium/Proton exchangers - Homo sapiens
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:425959] Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter [LiteratureReference:425997] Molecular cloning, tissue distribution, and functional expression of the human Na(+)/H(+) exchanger NHE2 [LiteratureReference:425968] Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3 [LiteratureReference:425996] Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE5) from human brain
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Na+/H+ exchanger transport (at cell membrane)
orthologousEvent	[Reaction:R-SCE-425994] Na+/H+ exchanger transport (at cell membrane) - Saccharomyces cerevisiae [Reaction:R-SPO-425994] Na+/H+ exchanger transport (at cell membrane) - Schizosaccharomyces pombe [Reaction:R-DDI-425994] Na+/H+ exchanger transport (at cell membrane) - Dictyostelium discoideum [Reaction:R-CEL-425994] Na+/H+ exchanger transport (at cell membrane) - Caenorhabditis elegans [Reaction:R-DME-425994] Na+/H+ exchanger transport (at cell membrane) - Drosophila melanogaster [Reaction:R-GGA-425994] Na+/H+ exchanger transport (at cell membrane) - Gallus gallus [Reaction:R-XTR-425994] Na+/H+ exchanger transport (at cell membrane) - Xenopus tropicalis [Reaction:R-DRE-425994] Na+/H+ exchanger transport (at cell membrane) - Danio rerio [Reaction:R-SSC-425994] Na+/H+ exchanger transport (at cell membrane) - Sus scrofa [Reaction:R-BTA-425994] Na+/H+ exchanger transport (at cell membrane) - Bos taurus [Reaction:R-CFA-425994] Na+/H+ exchanger transport (at cell membrane) - Canis familiaris [Reaction:R-RNO-425994] Na+/H+ exchanger transport (at cell membrane) - Rattus norvegicus [Reaction:R-MMU-425994] Na+/H+ exchanger transport (at cell membrane) - Mus musculus
output	[SimpleEntity:R-ALL-351626] H+ [extracellular region] [SimpleEntity:R-ALL-83910] Na+ [cytosol]
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:433651] He, L, 2009-08-24
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-425994
summation	[Summation:425993] NHE1 (SLC9A1) is present in most cells and is the most exten...

Referrals

(hasEvent)

[Pathway:R-HSA-425986] Sodium/Proton exchangers

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