Reactome | SUMOylation of DAXX with SUMO1

Schema > Reaction > Entries

SUMOylation of DAXX with SUMO1 Show undefined attributes

authored	[InstanceEdit:4085380] May, B, 2013-08-05
catalystActivity	[CatalystActivity:2997650] SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9644118] SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm] Identification of a substrate recognition site on Ubc9
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:4086035] May, B, 2013-08-06
dbId	4085992
displayName	SUMOylation of DAXX with SUMO1
edited	[InstanceEdit:4085380] May, B, 2013-08-05
eventOf	[Pathway:R-HSA-3899300] SUMOylation of transcription cofactors - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-3222068] DAXX [nucleoplasm] 2 × [Complex:R-HSA-2993783] SUMO1:C93-UBE2I [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:4086089] Modification of Daxx by small ubiquitin-related modifier-1 [LiteratureReference:4086094] Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors [LiteratureReference:4086048] The insulin-sensitive glucose transporter, GLUT4, interacts physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	SUMOylation of DAXX with SUMO1
orthologousEvent	[Reaction:R-DDI-4085992] SUMOylation of DAXX with SUMO1 - Dictyostelium discoideum [Reaction:R-GGA-4085992] SUMOylation of DAXX with SUMO1 - Gallus gallus [Reaction:R-SSC-4085992] SUMOylation of DAXX with SUMO1 - Sus scrofa [Reaction:R-BTA-4085992] SUMOylation of DAXX with SUMO1 - Bos taurus [Reaction:R-RNO-4085992] SUMOylation of DAXX with SUMO1 - Rattus norvegicus [Reaction:R-MMU-4085992] SUMOylation of DAXX with SUMO1 - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-4086086] monoSUMO1-K630,K631-DAXX [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-HSA-912481] UBE2I [nucleoplasm]
precedingEvent	[Reaction:R-HSA-2993780] Transfer of SUMO1 from E1 to UBE2I (UBC9) - Homo sapiens
releaseDate	2018-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608076] Niskanen, Einari, 2018-05-09 [InstanceEdit:9615865] Niskanen, Einari, 2018-08-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-4085992
summation	[Summation:4086097] DAXX is SUMOylated at lysine-630 and lysine-631 with SUMO1 (...
updateTrackers	[UpdateTracker:9775004] Update Tracker - [Reaction:4085992] SUMOylation of DAXX with SUMO1 - v80:[add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9775004] Update Tracker - [Reaction:4085992] SUMOylation of DAXX with SUMO1 - v80:[add_removeOutput]
(hasEvent)	[Pathway:R-HSA-3899300] SUMOylation of transcription cofactors