Reactome | EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane]

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EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:3928575] protein serine/threonine kinase activity of EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-3928625] PAKs autophosphorylate - Homo sapiens
created	[InstanceEdit:3928506] Garapati, P V, 2013-07-22
dbId	3928537
displayName	EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane]
entityOnOtherCell	[DefinedSet:R-HSA-3928335] EPHBs [plasma membrane] - Homo sapiens
hasComponent	[Complex:R-HSA-3928560] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] [CandidateSet:R-HSA-442619] PAK1/3, 2 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - Mus musculus [Complex:R-RNO-3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - Canis familiaris [Complex:R-BTA-3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - Bos taurus [Complex:R-SSC-3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - Sus scrofa [Complex:R-DRE-3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - Danio rerio [Complex:R-XTR-3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - Gallus gallus [Complex:R-DME-3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - Caenorhabditis elegans
isChimeric	false
maxDepth	9
modified	[InstanceEdit:5340174] Garapati, P V, 2014-03-12
name	EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3
producedByEvent	[Reaction:R-HSA-3928641] PAK binds RAC and bPIX - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-3928537
updateTrackers	[UpdateTracker:9896118] Update Tracker - [Complex:3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - v60:[updateContainedComponent] [UpdateTracker:9895487] Update Tracker - [Complex:3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - v59:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9896118] Update Tracker - [Complex:3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - v60:[updateContainedComponent] [UpdateTracker:9895487] Update Tracker - [Complex:3928537] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] - v59:[updateContainedComponent]
(input)	[Reaction:R-HSA-3928625] PAKs autophosphorylate
(physicalEntity)	[CatalystActivity:3928575] protein serine/threonine kinase activity of EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane]
(output)	[Reaction:R-HSA-3928641] PAK binds RAC and bPIX

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