Reactome | Dephosphorylation of AKT by PP2A

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Dephosphorylation of AKT by PP2A Show undefined attributes

authored	[InstanceEdit:388810] Garapati, P V, 2008-12-16 11:12:19
catalystActivity	[CatalystActivity:390328] phosphatidate phosphatase activity of PP2A [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:390332] Garapati, P V, 2009-01-26 10:07:27
dbId	390329
displayName	Dephosphorylation of AKT by PP2A
edited	[InstanceEdit:388810] Garapati, P V, 2008-12-16 11:12:19
eventOf	[Pathway:R-HSA-389513] CTLA4 inhibitory signaling - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [CandidateSet:R-HSA-202074] p-T,p-S-AKT [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:425541] Structure-Function analysis of the CTLA-4 interaction with PP2A
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	Dephosphorylation of AKT by PP2A
orthologousEvent	[Reaction:R-SCE-390329] Dephosphorylation of AKT by PP2A - Saccharomyces cerevisiae [Reaction:R-SPO-390329] Dephosphorylation of AKT by PP2A - Schizosaccharomyces pombe [Reaction:R-DDI-390329] Dephosphorylation of AKT by PP2A - Dictyostelium discoideum [Reaction:R-CEL-390329] Dephosphorylation of AKT by PP2A - Caenorhabditis elegans [Reaction:R-DME-390329] Dephosphorylation of AKT by PP2A - Drosophila melanogaster [Reaction:R-RNO-390329] Dephosphorylation of AKT by PP2A - Rattus norvegicus [Reaction:R-MMU-390329] Dephosphorylation of AKT by PP2A - Mus musculus
output	[CandidateSet:R-HSA-202088] AKT [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-HSA-388833] Phosphorylation of CTLA-4 - Homo sapiens
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:422514] Bluestone, JA, Esensten, J, 2009-06-01 18:47:33
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-390329
summation	[Summation:390205] When CTLA4 is engaged by B7 molecules, PP2A disassociates fr...

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(hasEvent)

[Pathway:R-HSA-389513] CTLA4 inhibitory signaling