Reactome | CXCR4,7:CXCL12 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:374171] Jassal, Bijay, 2008-07-28
dbId	374203
displayName	CXCR4,7:CXCL12 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-2980693] CXCL12(22-93) [extracellular region] [DefinedSet:R-HSA-374120] CXCR4,7 [plasma membrane]
inDisease	false
includedLocation	[Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-374203] CXCR4,7:CXCL12 [plasma membrane] - Mus musculus [Complex:R-RNO-374203] CXCR4,7:CXCL12 [plasma membrane] - Rattus norvegicus [Complex:R-SSC-374203] CXCR4,7:CXCL12 [plasma membrane] - Sus scrofa [Complex:R-DRE-374203] CXCR4,7:CXCL12 [plasma membrane] - Danio rerio [Complex:R-GGA-374203] CXCR4,7:CXCL12 [plasma membrane] - Gallus gallus
maxDepth	3
memberOf	[DefinedSet:R-HSA-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Homo sapiens
modified	[InstanceEdit:2980692] Jupe, S, 2013-01-11
name	CXCR4,7:CXCL12
producedByEvent	[Reaction:R-HSA-374214] Receptors CXCR4 and 7 bind CXCL12 ligand - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-374203
updateTrackers	[UpdateTracker:9875516] Update Tracker - [Complex:374203] CXCR4,7:CXCL12 [plasma membrane] - v44:[add_removeHasComponent, updateContainedComponent] [UpdateTracker:9868726] Update Tracker - [Complex:374203] CXCR4,7:CXCL12 [plasma membrane] - v32:[modifyName, updateContainedComponent]

(updatedInstance)	[UpdateTracker:9875516] Update Tracker - [Complex:374203] CXCR4,7:CXCL12 [plasma membrane] - v44:[add_removeHasComponent, updateContainedComponent] [UpdateTracker:9868726] Update Tracker - [Complex:374203] CXCR4,7:CXCL12 [plasma membrane] - v32:[modifyName, updateContainedComponent]
(output)	[Reaction:R-HSA-374214] Receptors CXCR4 and 7 bind CXCL12 ligand
(hasMember)	[DefinedSet:R-HSA-380091] Ligand:GPCR complexes that activate Gi [plasma membrane]