Reactome | p-4S,T185,T186-TGFBR1 D269_Q324del [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-3656516] p-4S-T185,T186-TGFBR1 KD Mutants [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:3656507] Orlic-Milacic, M, 2013-06-05
crossReference	[DatabaseIdentifier:12021367] Mondo:0007566
dbId	3656509
disease	[Disease:1500689] cancer [Disease:3656325] Ferguson-Smith tumor
displayName	p-4S,T185,T186-TGFBR1 D269_Q324del [plasma membrane]
endCoordinate	503
hasModifiedResidue	[FragmentDeletionModification:3656388] Deletion of residues 269 to 324 [ModifiedResidue:170853] O-phospho-L-serine at 165 [ModifiedResidue:178237] O-phospho-L-threonine at 185 [ModifiedResidue:178234] O-phospho-L-threonine at 186 [ModifiedResidue:178238] O-phospho-L-serine at 187 [ModifiedResidue:178241] O-phospho-L-serine at 189 [ModifiedResidue:178239] O-phospho-L-serine at 191
inDisease	true
literatureReference	[LiteratureReference:3656346] Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1
maxDepth	1
modified	[InstanceEdit:5624358] Jupe, Steve, 2014-09-26
name	p-4S,T185,T186-TGFBR1 D269_Q324del
referenceEntity	[ReferenceGeneProduct:uniprot:P36897] UniProt:P36897 TGFBR1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-3656509
startCoordinate	34

(hasCandidate)

Cite Us!