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Schema
>
FailedReaction
>
Entries
Defective B4GALT1 does not transfer Gal to the keratan chain
Show undefined attributes
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authored
[InstanceEdit:3656262] Jassal, B, 2013-05-31
catalystActivity
[CatalystActivity:9631947] beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity of B4GALT1 R345Kfs*6 [Golgi membrane]
category
transition
compartment
[Compartment:17963] Golgi lumen
[Compartment:20699] Golgi membrane
created
[InstanceEdit:3656245] Jassal, B, 2013-05-31
crossReference
[DatabaseIdentifier:12020881] Mondo:0005501
dbId
3656230
disease
[Disease:3656242] congenital disorder of glycosylation type II
displayName
Defective B4GALT1 does not transfer Gal to the keratan chain
edited
[InstanceEdit:3656245] Jassal, B, 2013-05-31
entityFunctionalStatus
[EntityFunctionalStatus:3656429] loss_of_function of B4GALT1 R345Kfs*6 [Golgi membrane]
eventOf
[Pathway:R-HSA-3656244] Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) - Homo sapiens
input
[DefinedSet:R-HSA-2046187] Keratan(1)-PG [Golgi lumen]
[SimpleEntity:R-ALL-735682] UDP-Gal [Golgi lumen]
isChimeric
false
isInDisease
true
isInferred
false
literatureReference
[LiteratureReference:1015828] Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name
Defective B4GALT1 does not transfer Gal to the keratan chain
normalReaction
[Reaction:R-HSA-2046265] B4GALTs transfer Gal to the keratan chain
releaseDate
2014-09-30
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:5607064] Spillmann, Dorothe, 2014-07-09
schemaClass
FailedReaction
species
[Species:48887] Homo sapiens
stId
R-HSA-3656230
summation
[Summation:3656433] The family of beta 4-galactosyltransferases (B4GALTs) is com...
updateTrackers
[UpdateTracker:9778255] Update Tracker - [FailedReaction:3656230] Defective B4GALT1 does not transfer Gal to the keratan chain - v68:[addCatalystActivity]
[UpdateTracker:9779722] Update Tracker - [FailedReaction:3656230] Defective B4GALT1 does not transfer Gal to the keratan chain - v64:[add_removeInput]
[UpdateTracker:9785798] Update Tracker - [FailedReaction:3656230] Defective B4GALT1 does not transfer Gal to the keratan chain - v51:[modifyText]
[UpdateTracker:9782391] Update Tracker - [FailedReaction:3656230] Defective B4GALT1 does not transfer Gal to the keratan chain - v59:[add_removeLiteratureReference]
Referrals
(updatedInstance)
[UpdateTracker:9778255] Update Tracker - [FailedReaction:3656230] Defective B4GALT1 does not transfer Gal to the keratan chain - v68:[addCatalystActivity]
[UpdateTracker:9779722] Update Tracker - [FailedReaction:3656230] Defective B4GALT1 does not transfer Gal to the keratan chain - v64:[add_removeInput]
[UpdateTracker:9785798] Update Tracker - [FailedReaction:3656230] Defective B4GALT1 does not transfer Gal to the keratan chain - v51:[modifyText]
[UpdateTracker:9782391] Update Tracker - [FailedReaction:3656230] Defective B4GALT1 does not transfer Gal to the keratan chain - v59:[add_removeLiteratureReference]
(hasEvent)
[Pathway:R-HSA-3656244] Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
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