Reactome | USP34 deubiquitinates AXIN1,AXIN2

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USP34 deubiquitinates AXIN1,AXIN2 Show undefined attributes

authored	[InstanceEdit:3632861] Rothfels, K, 2013-05-27
catalystActivity	[CatalystActivity:3640873] cysteine-type deubiquitinase activity of USP34 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:3640871] Rothfels, K, 2013-05-29
dbId	3640872
displayName	USP34 deubiquitinates AXIN1,AXIN2
edited	[InstanceEdit:4655138] Gillespie, ME, 2013-10-02
eventOf	[Pathway:R-HSA-201681] TCF dependent signaling in response to WNT - Homo sapiens [Pathway:R-HSA-5689880] Ub-specific processing proteases - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-HSA-3640854] Ub-RibC-AXIN:TNKS:RNF146 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3640801] The ubiquitin-specific protease USP34 regulates axin stability and Wnt/?-catenin signaling
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	USP34 deubiquitinates AXIN1,AXIN2
orthologousEvent	[Reaction:R-GGA-3640872] USP34 deubiquitinates AXIN1,AXIN2 - Gallus gallus [Reaction:R-BTA-3640872] USP34 deubiquitinates AXIN1,AXIN2 - Bos taurus [Reaction:R-CFA-3640872] USP34 deubiquitinates AXIN1,AXIN2 - Canis familiaris [Reaction:R-RNO-3640872] USP34 deubiquitinates AXIN1,AXIN2 - Rattus norvegicus [Reaction:R-MMU-3640872] USP34 deubiquitinates AXIN1,AXIN2 - Mus musculus
output	[Complex:R-HSA-3640845] RibC-AXIN:TNKS:RNF146 [cytosol] [DefinedSet:R-HSA-113595] Ub [cytosol]
precedingEvent	[Reaction:R-HSA-3640861] RNF146 ubiquitinates ADP-ribosylated AXIN - Homo sapiens
releaseDate	2014-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5251465] Rajakulendran, Nishani, 2014-01-22 [InstanceEdit:5323527] van Amerongen, R, 2014-02-14 [InstanceEdit:5368564] Kikuchi, Akira, 2014-04-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-3640872
summation	[Summation:3640870] UBP34 (also known as USP34) is a ubiquitin protease that co-...

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