Reactome | ZNF521 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9832904] ZNF521:SOX1 gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-9832854] POU3F1:ZNF521:PAX6 gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9832908] ZNF521 binds the SOX1 gene - Homo sapiens [Reaction:R-HSA-9008137] RUNX2 binds ZNF521 and HDAC3 - Homo sapiens [Reaction:R-HSA-9832823] POU3F1 and ZNF521 bind the PAX6 gene - Homo sapiens
created	[InstanceEdit:3222323] Orlic-Milacic, M, 2013-03-19
dbId	3222324
displayName	ZNF521 [nucleoplasm]
endCoordinate	1311
inDisease	false
maxDepth	1
modified	[InstanceEdit:9008154] Orlic-Milacic, Marija, 2017-06-07
name	ZNF521 Zinc finger protein 521 ZFP521 Early hematopoietic zinc finger protein LYST-interacting protein 3 EHZF LIP3
producedByEvent	[BlackBoxEvent:R-HSA-9832834] Expression of ZNF521 in anterior neural plate - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q96K83] UniProt:Q96K83 ZNF521
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-3222324
startCoordinate	1

(activeUnit)	[PositiveGeneExpressionRegulation:9832814] Positive gene expression regulation by 'POU3F1:ZNF521:PAX6 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9832903] Positive gene expression regulation by 'ZNF521:SOX1 gene [nucleoplasm]' [NegativeRegulation:R-HSA-9008166] Negative regulation by 'RUNX2:ZNF521:HDAC3 [nucleoplasm]'
(hasComponent)	[Complex:R-HSA-9832854] POU3F1:ZNF521:PAX6 gene [nucleoplasm] [Complex:R-HSA-9832904] ZNF521:SOX1 gene [nucleoplasm] [Complex:R-HSA-9008155] RUNX2:ZNF521:HDAC3 [nucleoplasm]
(input)	[Reaction:R-HSA-9832823] POU3F1 and ZNF521 bind the PAX6 gene [Reaction:R-HSA-9832908] ZNF521 binds the SOX1 gene [Reaction:R-HSA-9008137] RUNX2 binds ZNF521 and HDAC3
(output)	[BlackBoxEvent:R-HSA-9832834] Expression of ZNF521 in anterior neural plate

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